CHAPTER 9: Catalysis at the Organic Ligands

Crystalline metal organic frameworks containing catalytically active organic linkers or ancillary ligands (i.e., catalysts at the organic ligands) are an intriguing sub‐set of heterogeneous catalysts. These catalysts are atomically defined and offer a platform to readily designed single‐site catalysts. The literature encompasses approximately fifty experimental examples from which we highlight a handful of what we perceive to be,key conceptual papers. It is clear that many of the attractive visions for MOF catalysts—including, “multi‐catalyst architectures”, “metal coordination environments that can be achieved in no other ways” and “reactivity‐defining microenvironments”—are starting to be realized.