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SPR Organophosphorus Chemistry
Organophosphorus Chemistry
Edited by
David W Allen;
David W Allen
Sheffield Hallam University, UK
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John C Tebby
John C Tebby
Sheffield Hallam University, UK
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Volume
42
Hardback ISBN:
978-1-84973-584-1
PDF ISBN:
978-1-84973-770-8
No. of Pages:
384
Published online:
24 May 2013
Published in print:
29 Apr 2013
Book Chapter
Nucleotides and nucleic acids; oligo‐ and polynucleotides
By
David Loakes
David Loakes
MRC
Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge, CB2 0QH
UK
dml@mrc‐lmb.cam.ac.uk
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Published:29 Apr 2013
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Page range:
285 - 353
Citation
D. Loakes, in Organophosphorus Chemistry, ed. D. W. Allen, D. Loakes, and J. C. Tebby, The Royal Society of Chemistry, 2013, vol. 42, pp. 285-353.
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As in previous years, modified oligonucleotides continue to attract much research. The scope for modifying oligonucleotides is quite broad, nucleobase, sugar or the internucleotide linkage, and a combination of each. This review covers literature for 2011 ealing with modified oligonucleotides, though unlike previous years the sections on aptamers and ribozymes, and nucleic structures are excluded, but will be dealt with in the next volume.
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