Functional Polymers for Nanomedicine
Interest in the application of nanotechnology to medicine has surged in recent years and could transform the way we diagnose, treat and prevent diseases such as cancer. However, the clinical success of nanomedicine is limited because of problems with toxicity and therapeutic efficacy. To overcome this it is essential to produce new nanosystems with specific functions, which can be achieved by designing new polymers with particular properties that can be used for nanomedicine. Functional Polymers for Nanomedicine provides a complete overview of the different strategies for designing polymers for nanomedicine applications. The first part of the book looks at the current problems and direction in nanomedicine including a review of current design and targeting of nanocarriers. The second part explores the design of polymers with different functions including hyperbranched polymers, polymersomes, polysaccharides, polymeric micelles and zwitterionic polymers and their applications in gene therapy and drug delivery. This timely book is edited by a leading scientist in nanomedicine and provides a suitable introduction and reference source for advanced undergraduates, postgraduates and academic and industrial researchers in polymer science, nanotechnology and pharmacy interested in materials for medical applications.
Royal Society of Chemistry and Royal Society of Chemistry, Functional Polymers for Nanomedicine, The Royal Society of Chemistry, 2013.
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Targeted Drug Delivery in Oncology: Current Paradigm and Challengesp1-19ByDarren Lars Stirland;Darren Lars StirlandDepartment of Bioengineering, College of Engineering, University of UtahSalt Lake CityUSA,UT 84108Search for other works by this author on:You Han BaeYou Han BaeDepartment of Pharmaceutics and Pharmaceutical Chemistry, College of Pharmacy, University of UtahSalt Lake CityUSA,UT 84108Search for other works by this author on:
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Chapter 2: Targeted Nanomedicines: Challenges and Opportunitiesp20-31ByJinming GaoJinming GaoDepartment of Pharmacology, Harold C. Simmons Comprehensive Cancer Centre, University of Texas Southwestern Medical Center at DallasDallasTX 75390USA[email protected]Search for other works by this author on:
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Chapter 3: Rational Design of Translational Nanocarriersp32-62ByQihang Sun;Qihang SunDepartment of Chemical and Petroleum Engineering, Soft Materials Laboratory, University of WyomingLaramieWY 82071USASearch for other works by this author on:Maciej Radosz;Maciej RadoszDepartment of Chemical and Petroleum Engineering, Soft Materials Laboratory, University of WyomingLaramieWY 82071USASearch for other works by this author on:Youqing ShenYouqing ShenCenter for Bionanoengineering and State Key Laboratory of Chemical Engineering, Department of Chemical and Biological Engineering, Zhejiang UniversityHangzhou 310027P. R. China[email protected]Search for other works by this author on:
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Chapter 4: Functional Polymers for Gene Deliveryp63-120ByXian-Zheng ZhangXian-Zheng ZhangKey Laboratory of Biomedical Polymers of Ministry of Education & Department of Chemistry, Wuhan UniversityWuhan430072P. R. China[email protected]Search for other works by this author on:
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Chapter 5: Functional Hyperbranched Polymers for Drug and Gene Deliveryp121-143ByXinyuan ZhuXinyuan ZhuShanghai Jiao Tong University, School of Chemistry and Chemical Engineering, State Key Laboratory of Metal Matrix CompositesShanghai 200240P. R. China[email protected]Search for other works by this author on:
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Chapter 6: Functional Polymersomes for Controlled Drug Deliveryp144-157ByZhiyuan ZhongZhiyuan ZhongBiomedical Polymers Laboratory, and Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application, Department of Polymer Science and Engineering, College of Chemistry, Chemical Engineering and Materials Science, Soochow UniversitySuzhou 215123P. R. China[email protected]Search for other works by this author on:
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Chapter 7: Polymeric Micelle-Based Nanomedicine for siRNA Deliveryp158-189ByJun WangJun WangCAS Key Laboratory of Brain Function and Disease, and School of Life Sciences, University of Science and Technology of ChinaHefei, Anhui 230027P. R. China[email protected]Search for other works by this author on:
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Chapter 8: Polysaccharide/Polynucleotide Complexes for Cell-Specific DNA Deliveryp190-206ByShinichi Mochizuki;Shinichi MochizukiDepartment of Chemistry and Biochemistry, The University of Kitakyushu, 1-1, Hibikino, Wakamatsu-ku, KitakyushuFukuoka, 808-0135Japan[email protected]Search for other works by this author on:Kazuo SakuraiKazuo SakuraiDepartment of Chemistry and Biochemistry, The University of Kitakyushu, 1-1, Hibikino, Wakamatsu-ku, KitakyushuFukuoka, 808-0135Japan[email protected]CREST, Japan Science and Technology Agency, 4-1-8, Honcho, KawaguchishiSaitama, 332-0012JapanSearch for other works by this author on:
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Chapter 9: Design of Complex Micelles for Drug Deliveryp207-226ByLinqi ShiLinqi ShiKey Laboratory of Functional Polymer Materials, Ministry of Education, and Institute of Polymer Chemistry, Nankai UniversityTianjin 300071P. R. China[email protected]Search for other works by this author on:
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Chapter 10: Zwitterionic Polymers for Targeted Drug Deliveryp227-244ByShengFu ChenShengFu ChenState Key Laboratory of Chemical Engineering, Department of Chemical and Biological Engineering, Zhejiang UniversityHangzhou 310027P. R. China[email protected]Search for other works by this author on:
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Chapter 11: Polymer-Based Prodrugs for Cancer Chemotherapyp245-260ByQihang Sun;Qihang SunDepartment of Chemical and Petroleum Engineering, Soft Materials Laboratory, University of WyomingLaramieWY 82071USA[email protected]Search for other works by this author on:Jinqiang Wang;Jinqiang WangCenter for Bionanoengineering and State Key Laboratory of Chemical Engineering, Department of Chemical and Biological Engineering, Zhejiang UniversityHangzhou 310027P. R. ChinaSearch for other works by this author on:Maciej Radosz;Maciej RadoszDepartment of Chemical and Petroleum Engineering, Soft Materials Laboratory, University of WyomingLaramieWY 82071USA[email protected]Search for other works by this author on:Youqing ShenYouqing ShenCenter for Bionanoengineering and State Key Laboratory of Chemical Engineering, Department of Chemical and Biological Engineering, Zhejiang UniversityHangzhou 310027P. R. ChinaSearch for other works by this author on:
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Chapter 12: Nonviral Vector Recombinant Mesenchymal Stem Cells: A Promising Targeted-Delivery Vehicle in Cancer Gene Therapyp261-280ByYu-Lan Hu;Yu-Lan HuInstitute of Pharmaceutics, College of Pharmaceutical Sciences, Zhejiang UniversityP. R. China[email protected]Search for other works by this author on:Ying-Hua Fu;Ying-Hua FuDepartment of Pharmaceutics, School of Medicine, Jiaxing UniversityP. R. ChinaSearch for other works by this author on:Yasuhiko Tabata;Yasuhiko TabataDepartment of Biomaterials, Institute for Frontier Medical Sciences, Kyoto UniversityJapanSearch for other works by this author on:Jian-Qing GaoJian-Qing GaoInstitute of Pharmaceutics, College of Pharmaceutical Sciences, Zhejiang UniversityP. R. China[email protected]Search for other works by this author on:
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Chapter 13: Near-Critical Micellization for Nanomedicine: Enhanced Drug Loading, Reduced Burst Releasep281-301ByJade Green;Jade GreenDepartment of Chemical and Petroleum Engineering, Soft Materials Laboratory, University of WyomingLaramieWY 82071USA[email protected]Search for other works by this author on:Maciej Radosz;Maciej RadoszDepartment of Chemical and Petroleum Engineering, Soft Materials Laboratory, University of WyomingLaramieWY 82071USA[email protected]Search for other works by this author on:Youqing ShenYouqing ShenCenter for Bionanoengineering and State Key Laboratory of Chemical Engineering, Department of Chemical and Biological Engineering, Zhejiang UniversityHangzhou 310027P. R. ChinaSearch for other works by this author on:
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