Supramolecular Systems in Biomedical Fields
Non-covalent interactions, which are the heart of supramolecular chemistry are also the basis of most important functions of living systems. The ability to apply supramolecular chemistry principles to the life sciences, such as designing synthetic host compounds to selectively interact within biological targets, has gained wide appeal due the vast number of potential applications.
Supramolecular Systems for Biomedical Fields provides in sixteen chapters a comprehensive overview of these applications. Each chapter covers a specific topic and is written by internationally renowned experts in that area. Sensing of bioactive inorganic ions and organic substrates is the focus of several contributions, as well as interactions with proteins and nucleic acids. Specific chapters are devoted to cyclodextrins, calixarenes and cucurbiturils as most frequently used receptors, including applications such as drug delivery and protection, gene transfer and others. Other chapters address the use of combinatorial libraries, molecular imprinting techniques, enzyme assays, supramolecular gels, bioimaging, drug activation, photodynamic therapy, and antitumour metal complexes.
This timely publication will appeal to graduate students and researchers from chemical, pharmaceutical, biological, and medicinal fields interested in the supramolecular chemistry of biological systems and their practical potentials.
Supramolecular Systems in Biomedical Fields, The Royal Society of Chemistry, 2013.
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Table of contents
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CHAPTER 1: Introductionp1-6ByHans-Jörg SchneiderHans-Jörg SchneiderSearch for other works by this author on:
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CHAPTER 2: Signalling Techniques in Supramolecular Systemsp7-37ByLeonard J. PrinsLeonard J. PrinsSearch for other works by this author on:
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CHAPTER 3: Metal Ion Sensing for Biomedical Usesp38-67ByCarl J. MalliaCarl J. MalliaSearch for other works by this author on:
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CHAPTER 4: Complexation of Biomedically Important Organic Compoundsp68-93ByHans-Jörg SchneiderHans-Jörg SchneiderSearch for other works by this author on:
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CHAPTER 5: Cyclodextrins for Pharmaceutical and Biomedical Applicationsp94-139ByC. Ortiz Mellet;C. Ortiz MelletUniversity of SevillaFaculty of Chemistry, Department of Organic Chemistry, C/ Prof. García González, Sevilla, E-41012Spain[email protected]Search for other works by this author on:J. M. García Fernández;J. M. García FernándezInstitute for Chemical Research (IIQ)CSIC – University of Sevilla, Avda. Américo Vespucio 49, Sevilla, E-41092Spain[email protected]Search for other works by this author on:J. M. BenitoJ. M. BenitoInstitute for Chemical Research (IIQ)CSIC – University of Sevilla, Avda. Américo Vespucio 49, Sevilla, E-41092Spain[email protected]Search for other works by this author on:
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CHAPTER 6: Interactions of Calix[n]arenes and Other Organic Supramolecular Systems with Proteinsp140-163ByFlorent Perret;Florent PerretUniversité Lyon 1ICBMS UMR-CNRS 5246, CSAp, Villeurbanne, F69622FranceSearch for other works by this author on:Anthony W. ColemanAnthony W. ColemanI.I.S.University of Tokyo, Tokyo 153-8505JapanSearch for other works by this author on:
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CHAPTER 7: Cucurbiturils in Drug Delivery And For Biomedical Applicationsp164-212ByNa’il Saleh;Na’il SalehDepartment of ChemistryCollege of Science, UAE University, P.O. Box 15551, Al-AinUnited Arab Emirates[email protected][email protected]Search for other works by this author on:Indrajit Ghosh;Indrajit GhoshSchool of Engineering and ScienceJacobs University Bremen, Campus Ring 1, D-28759, BremenGermany[email protected]Search for other works by this author on:Werner M. NauWerner M. NauSchool of Engineering and ScienceJacobs University Bremen, Campus Ring 1, D-28759, BremenGermany[email protected]Search for other works by this author on:
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CHAPTER 8: Nucleic Acids as Supramolecular Targetsp213-259ByEnrique García-España;Enrique García-EspañaUniversitat de ValènciaInstituto de Ciencia Molecular, 46980 Paterna (Valencia)SpainSearch for other works by this author on:Ivo Piantanida;Ivo PiantanidaRudjer Boskovic Institute HR-10002 ZagrebSearch for other works by this author on:Hans-Jörg SchneiderHans-Jörg SchneiderUniversität des SaarlandesFR Organische Chemie, SaarbrückenGermany[email protected][email protected][email protected]Search for other works by this author on:
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CHAPTER 9: Biomolecular Interactions of Platinum Complexesp260-299ByBenjamin W. Harper;Benjamin W. HarperNanoscale Organisation and Dynamics GroupSchool of Science and Health, University of Western Sydney, Locked Bag 2579, Penrith South DC, NSW, 1797Australia[email protected]Search for other works by this author on:Feng Li;Feng LiNanoscale Organisation and Dynamics GroupSchool of Science and Health, University of Western Sydney, Locked Bag 2579, Penrith South DC, NSW, 1797Australia[email protected]Search for other works by this author on:Rhys Beard;Rhys BeardNanoscale Organisation and Dynamics GroupSchool of Science and Health, University of Western Sydney, Locked Bag 2579, Penrith South DC, NSW, 1797Australia[email protected]Search for other works by this author on:K. Benjamin Garbutcheon-Singh;K. Benjamin Garbutcheon-SinghNanoscale Organisation and Dynamics GroupSchool of Science and Health, University of Western Sydney, Locked Bag 2579, Penrith South DC, NSW, 1797Australia[email protected]Search for other works by this author on:Neville S. Ng;Neville S. NgNanoscale Organisation and Dynamics GroupSchool of Science and Health, University of Western Sydney, Locked Bag 2579, Penrith South DC, NSW, 1797Australia[email protected]Search for other works by this author on:Janice R. Aldrich-WrightJanice R. Aldrich-WrightNanoscale Organisation and Dynamics GroupSchool of Science and Health, University of Western Sydney, Locked Bag 2579, Penrith South DC, NSW, 1797Australia[email protected]Search for other works by this author on:
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CHAPTER 10: Supramolecular Metal Complexes for Imaging and Radiotherapyp300-330ByJürgen Schatz;Jürgen SchatzOrganic Chemistry 1, Department of Chemistry and PharmacyUniversity of Erlangen, Henkestraßig;e 42, 91054 ErlangenGermanySearch for other works by this author on:Daniel SchühleDaniel SchühleSearch for other works by this author on:
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CHAPTER 11: Supramolecular Gels for Pharmaceutical and Biomedical Applicationsp331-354ByJuan F. Miravet;Juan F. MiravetDepartament de Química Inorgànica i OrgànicaUniversitat Jaume I, 12071 CastellóSpain[email protected][email protected]Search for other works by this author on:Beatriu EscuderBeatriu EscuderDepartament de Química Inorgànica i OrgànicaUniversitat Jaume I, 12071 CastellóSpain[email protected][email protected]Search for other works by this author on:
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CHAPTER 12: Supramolecular Enzyme Assaysp355-396ByAndreas HennigAndreas HennigBAM Federal Institute for Materials Research and TestingRichard-Willstätter-Str. 11, D-12489 BerlinGermany[email protected]; [email protected]Search for other works by this author on:
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CHAPTER 13: Constitutional Dynamic Chemistry for Bioactive Compoundsp397-418ByYan Zhang;Yan ZhangKTH Royal Institute of TechnologyDepartment of Chemistry, Teknikringen 30, S-10044 StockholmSweden[email protected]Search for other works by this author on:Lei Hu;Lei HuKTH Royal Institute of TechnologyDepartment of Chemistry, Teknikringen 30, S-10044 StockholmSweden[email protected]Search for other works by this author on:Olof RamströmOlof RamströmKTH Royal Institute of TechnologyDepartment of Chemistry, Teknikringen 30, S-10044 StockholmSweden[email protected]Search for other works by this author on:
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CHAPTER 14: Molecular Imprinted Polymers for Biomedical Applicationsp419-450ByAdnan Mujahid;Adnan MujahidDepartment of Analytical ChemistryUniversity of Vienna, Waehringer Strasse 38 A-1090, ViennaAustriaInstitute of ChemistryUniversity of the Punjab, Quaid-i-Azam Campus, Lahore 54590Pakistan[email protected]Search for other works by this author on:Franz L. DickertFranz L. DickertDepartment of Analytical ChemistryUniversity of Vienna, Waehringer Strasse 38 A-1090, ViennaAustriaSearch for other works by this author on:
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CHAPTER 15: Supramolecular Approach for Tumor Imaging and Photodynamic Therapyp451-482ByAnurag Gupta;Anurag GuptaPhotodynamic Therapy Center, Department of Cell Stress BiologyRoswell Park Cancer Institute, Buffalo, NY 14263USA[email protected]Search for other works by this author on:Ravindra K. PandeyRavindra K. PandeyPhotodynamic Therapy Center, Department of Cell Stress BiologyRoswell Park Cancer Institute, Buffalo, NY 14263USA[email protected]Search for other works by this author on:
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CHAPTER 16: Designing Polymeric Binders for Pharmaceutical Applicationsp483-517ByNicolas Bertrand;Nicolas BertrandCurrent address: David H. Koch Institute for Integrative Cancer Research at Massachusetts Institute of Technology500 Main Street, Cambridge, MA 02139USASearch for other works by this author on:Patrick Colin;Patrick ColinFaculty of pharmacy, University of MontrealPO box 6128, Downtown station, Montréal, QC, H3C 3J7Canada[email protected]Search for other works by this author on:Maxime Ranger;Maxime RangerFaculty of pharmacy, University of MontrealPO box 6128, Downtown station, Montréal, QC, H3C 3J7Canada[email protected]Search for other works by this author on:Jeanne LeblondJeanne LeblondFaculty of pharmacy, University of MontrealPO box 6128, Downtown station, Montréal, QC, H3C 3J7Canada[email protected]Search for other works by this author on:
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