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Nanowire field-effect transistors (NWFETs) represent diverse and powerful nanostructures for achieving nanoscale electronic interfaces with biological systems. NWFETs exhibit exquisite sensitivity in chemical and biological detection and could form strongly coupled interfaces with cellular components. NWFETs also offer the hope of intervening with biological systems on a molecular scale for unprecedented studies of biophysical dynamics, in a nuanced way that has not been feasible up until this point.

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