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Formulation development plays a key role in advancing compounds from drug discovery through development to the market. In addition to suitably modifying the drug into a form in that it can be readily administered, formulations have a significant impact on enabling the bioavailability of the drug. Excipients and various formulation technologies have an impact on drug bioavailability via different mechanisms. Understanding the effect of formulations on these mechanisms is vital for designing an effective drug delivery system. The present chapter covers the key parameters that can be impacted by various formulation techniques to enable bioavailability.

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