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I personally want to thank all of the authors for providing their time and expertise in the completion of this book, and the Royal Society of Chemistry for giving me the opportunity to compile and edit this book on New Horizons in Predictive Drug Metabolism and Pharmacokinetics in the RSC Drug Discovery Series. A special thanks goes to Ayako Shinomiya Takei, who assisted me in the review and editing of the chapters. And finally, to the reader, I hope you will find this book of value to you in your quest for understanding the absorption, distribution, metabolism, elimination and pharmacokinetics of chemical entities, and as enjoyable to read as it was to compile.

This book is dedicated to my daughter Julia, my grandson Iain, and to the memory of my beloved Mary.

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