Skip Nav Destination
Food and Nutritional Components in Focus
Imidazole Dipeptides: Chemistry, Analysis, Function and EffectsCheck Access
Edited by
Victor R Preedy
Victor R Preedy
King's College London, UK
Search for other works by this author on:
Hardback ISBN:
978-1-84973-890-3
PDF ISBN:
978-1-78262-261-1
EPUB ISBN:
978-1-78262-655-8
No. of Pages:
602
Published online:
03 Aug 2015
Published in print:
13 Aug 2015
About this book
Carnosine and anserine are two common histidine-derived dipeptides, also known as imidazole dipeptides, found in muscle and brain tissues of animals. Their dietary and nutritional significance lies in their antioxidant properties and a number of investigators are looking at other health benefits of the compounds.
This volume surveys the current state of play in these and other areas of interest, including chemistry and biochemistry, immunology and cellular homeostasis. Chapters look in depth at some of the functions and effects in the body particularly with regard to exercise and fatigue, wound healing, cancer treatment and age-related diseases. Providing an up to date, interdisciplinary approach, this book is of great interest to researchers and professionals in chemistry, food science, nutrition, biochemistry, health sciences and sports sciences.
Imidazole Dipeptides: Chemistry, Analysis, Function and Effects, The Royal Society of Chemistry, 2015.
Download citation file:
Digital access
$279.00
Print format
Imidazole Dipeptides
$279.00
Table of contents
-
Carnosine in the Context of Histidine-Containing Dipeptidesp3-22ByGiulio VistoliGiulio VistoliDipartimento di Scienze Farmaceutiche, Università degli Studi di MilanoVia Mangiagalli, 25I-20133 MilanItaly[email protected]Search for other works by this author on:
-
CHAPTER 2: Carnosine and Its Homologs in Foodsp23-39ByPier Giorgio Peiretti;Pier Giorgio PeirettiInstitute of Science of Food Production, National Research CouncilVia L. da Vinci 4410095 GrugliascoItaly[email protected]Search for other works by this author on:Giorgia MeineriGiorgia MeineriDepartment of Veterinary Sciences, University of TorinoVia L. da Vinci 4410095 GrugliascoItalySearch for other works by this author on:
-
CHAPTER 3: The Chemistry of Imidazole Dipeptidesp43-60ByDaniel Perrone;Daniel PerroneLaboratório de Bioquímica Nutricional e de Alimentos, Departamento de Bioquímica, Instituto de Química, Universidade Federal do Rio de JaneiroAv. Athos da Silveira Ramos 149, CT, Bloco A, sala 528A21941-909Rio de JaneiroBrazil[email protected]Search for other works by this author on:Mariana Monteiro;Mariana MonteiroDepartamento de Nutrição Básica e Experimental, Instituto de Nutrição Josué de Castro, Universidade Federal do Rio de JaneiroAv. Carlos Chagas Filho, 373, CCS, bloco J, 2° andar, sala 1621941-902Rio de JaneiroBrazilSearch for other works by this author on:Vanessa Naciuk Castelo-BrancoVanessa Naciuk Castelo-BrancoDepartamento de Bromatologia, Faculdade de Farmácia, Universidade Federal FluminenseRua Mário Viana, 52324241-000NiteroiBrazilSearch for other works by this author on:
-
CHAPTER 4: The Chemistry of Carnosine Derivativesp61-83ByFrancesco Bellia;Francesco BelliaInstitute of Biostructure and Bioimaging, CNRV.le A.Doria 695125 CataniaItalySearch for other works by this author on:Enrico Rizzarelli;Enrico RizzarelliInstitute of Biostructure and Bioimaging, CNRV.le A.Doria 695125 CataniaItalySearch for other works by this author on:Graziella VecchioGraziella VecchioDipartimento di Scienze Chimiche, University of CataniaV.le A.Doria 695125 CataniaItaly[email protected]Search for other works by this author on:
-
CHAPTER 5: Chiral Carnosinep84-98ByDan Su;Dan SuThe National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herbal Medicine, Jiangxi University of Traditional Chinese Medicine56 Yangming RoadNanchang330006China[email protected]Search for other works by this author on:Yonggui SongYonggui SongThe National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herbal Medicine, Jiangxi University of Traditional Chinese Medicine56 Yangming RoadNanchang330006China[email protected]Search for other works by this author on:
-
CHAPTER 6: The Biochemistry of Enzymes Producing Carnosine and Anserinep99-117ByJakub Drozak;Jakub DrozakDepartment of Metabolic Regulation, Institute of Biochemistry, Faculty of Biology, University of WarsawMiecznikowa 102-096 WarsawPoland[email protected]Search for other works by this author on:Emile Van Schaftingen;Emile Van SchaftingenWelbio and Laboratory of Physiological Chemistry, de Duve Institute, Université catholique de LouvainAvenue Hippocrate 75, B1.75.08B-1200 BrusselsBelgium[email protected]Search for other works by this author on:Maria Veiga-da-CunhaMaria Veiga-da-CunhaWelbio and Laboratory of Physiological Chemistry, de Duve Institute, Université catholique de LouvainAvenue Hippocrate 75, B1.75.08B-1200 BrusselsBelgium[email protected]Search for other works by this author on:
-
CHAPTER 7: The Biochemistry of Anserine and Carnosine Degrading Enzymesp118-138ByShoji YamadaShoji YamadaLaboratory of Marine Biochemistry, Faculty of Fisheries, Kagoshima University4-50-20 ShimoarataKagoshimaJapan[email protected]Search for other works by this author on:
-
CHAPTER 8: Carnosine and Derivatives as Inhibitors of Protein Covalent Modifications Induced by Reactive Carbonyl Speciesp139-169ByMara Colzani;Mara ColzaniDepartment of Pharmaceutical Sciences, Università degli Studi di MilanoVia Mangiagalli 2520133 MilanItaly[email protected]Search for other works by this author on:Davide Garzon;Davide GarzonDepartment of Pharmaceutical Sciences, Università degli Studi di MilanoVia Mangiagalli 2520133 MilanItaly[email protected]Search for other works by this author on:Giancarlo AldiniGiancarlo AldiniDepartment of Pharmaceutical Sciences, Università degli Studi di MilanoVia Mangiagalli 2520133 MilanItaly[email protected]Search for other works by this author on:
-
CHAPTER 9: Antioxidant Activity of Imidazole Dipeptides – Prevention of DNA and Protein Degradationp170-188ByMasayoshi Takahashi;Masayoshi TakahashiReaction and Separation Engineering Lab, Food Engineering Division, National Food Research Institute, National Agriculture and Food Research Organization2-1-12 KannondaiTsukuba CityIbaraki Prefecture, 305-8642Japan[email protected]Search for other works by this author on:Shoji Hagiwara;Shoji HagiwaraReaction and Separation Engineering Lab, Food Engineering Division, National Food Research Institute, National Agriculture and Food Research Organization2-1-12 KannondaiTsukuba CityIbaraki Prefecture, 305-8642Japan[email protected]Search for other works by this author on:Hiroshi NabetaniHiroshi NabetaniDirector of Food Engineering Division, National Food Research Institute, National Agriculture and Food Research Organization2-1-12 KannondaiTsukubaIbaraki305-0031JapanSearch for other works by this author on:
-
CHAPTER 10: Liquid Chromatography Coupled to Tandem Mass Spectrometry to Analyze Imidazole Dipeptidesp191-213ByMaria-José Motilva;Maria-José MotilvaFood Technology Department, Agrotecnio Research Center, Escola Tecnica Superior d’Enginyeria Agraria (ETSEA), University of LleidaAv. Alcalde Rovira Roure 19125198 LleidaSpain[email protected]Search for other works by this author on:Alba Macià;Alba MaciàFood Technology Department, Agrotecnio Research Center, Escola Tecnica Superior d’Enginyeria Agraria (ETSEA), University of LleidaAv. Alcalde Rovira Roure 19125198 LleidaSpain[email protected]Search for other works by this author on:Alba Domínguez;Alba DomínguezPreparados Alimenticios S.A. subsidiary of Gallina Blanca Star Group. Plaza Europa 4108908 L’Hospitalet de LlobregatBarcelonaSpainSearch for other works by this author on:Agustín LabradorAgustín LabradorPreparados Alimenticios S.A. subsidiary of Gallina Blanca Star Group. Plaza Europa 4108908 L’Hospitalet de LlobregatBarcelonaSpainSearch for other works by this author on:
-
CHAPTER 11: Antioxidant Activity of Imidazole Dipeptidesp217-237ByEwa Biazik;Ewa BiazikDepartment of Animal Products Technology and Quality Management, Wrocław University of Environmental and Life SciencesChełmońskiego 37/4151-630 WrocławPoland[email protected]Department of Quality Analysis, Wrocław University of EconomicsKomandorska 118/12053-345 WrocławPolandSearch for other works by this author on:Wiesław KopećWiesław KopećDepartment of Animal Products Technology and Quality Management, Wrocław University of Environmental and Life SciencesChełmońskiego 37/4151-630 WrocławPoland[email protected]Search for other works by this author on:
-
CHAPTER 12: Inflammaging, Oxidative Stress and Carnosine: Role of Hormetic Vitagenesp238-256ByVittorio Calabrese;Vittorio CalabreseDepartment of Chemistry, University of CataniaViale Andrea Doria 6Catania 95125ItalySearch for other works by this author on:Sergio Davinelli;Sergio DavinelliDepartment of Medicine and Health Sciences, University of MoliseVia De Sanctis s.n.c.Campobasso 86100Italy[email protected]Search for other works by this author on:Maria Luca;Maria LucaDepartment of Chemistry, University of CataniaViale Andrea Doria 6Catania 95125ItalySearch for other works by this author on:Davide Zella;Davide ZellaDepartment of Biochemistry and Molecular Biology, University of Maryland-School of Medicine725 W. Lombard StreetBaltimoreMD 21201USASearch for other works by this author on:Edward J. Calabrese;Edward J. CalabreseDepartment Environmental Health Sciences, University of Massachusetts AmherstMorrill IAmherstMA 01003USASearch for other works by this author on:Giovanni ScapagniniGiovanni ScapagniniDepartment of Medicine and Health Sciences, University of MoliseVia De Sanctis s.n.c.Campobasso 86100Italy[email protected]Inter-University Consortium “Sannio Tech”Benevento, 82030ItalySearch for other works by this author on:
-
CHAPTER 13: Carnosine and the Control of Blood Glucosep257-276ByNobuaki Okumura;Nobuaki OkumuraInstitute for Protein Research, Osaka University3-2 Yamadaoka, SuitaOsaka 565-0871Japan[email protected]Search for other works by this author on:Mamoru Tanida;Mamoru TanidaInstitute for Protein Research, Osaka University, Department of Physiology II, Kanazawa Medical University1-1, Daigaku, Uchinada cho, Kahoku gunIshikawa 920-0293JapanSearch for other works by this author on:Akira Niijima;Akira NiijimaNiigata UniversityNiigata 951-8510JapanSearch for other works by this author on:Nobuo Tsuruoka;Nobuo TsuruokaInstitute for Health Care Science, Suntory Wellness LimitedOsaka 618-8503JapanSearch for other works by this author on:Yoshinobu Kiso;Yoshinobu KisoInstitute for Health Care Science, Suntory Wellness LimitedOsaka 618-8503JapanSearch for other works by this author on:Yuko Horii;Yuko HoriiANBAS Corporation, Institute for Protein Research, Osaka University4-12-17 Toyosaki, Kita-kuOsaka 531-0072JapanSearch for other works by this author on:Katsuya NagaiKatsuya NagaiANBAS Corporation, Institute for Protein Research, Osaka University4-12-17 Toyosaki, Kita-kuOsaka 531-0072JapanSearch for other works by this author on:
-
CHAPTER 14: β-Alanine, Muscle Carnosine and Exercisep277-294ByBryan Saunders;Bryan SaundersSchool of Physical Education and Sport, Laboratory of Applied Nutrition and Metabolism, University of São PauloAv. Prof. Mello de Moraes, 65, ButantãSão Paulo, SP 05508-030Brazil[email protected]Search for other works by this author on:Guilherme G. Artioli;Guilherme G. ArtioliSchool of Physical Education and Sport, Laboratory of Applied Nutrition and Metabolism, University of São PauloAv. Prof. Mello de Moraes, 65, ButantãSão Paulo, SP 05508-030Brazil[email protected]Search for other works by this author on:Craig Sale;Craig SaleBiomedical, Life and Health Sciences Research Centre, Nottingham Trent UniversityNottingham, NG11 8NSUKSearch for other works by this author on:Bruno GualanoBruno GualanoSchool of Physical Education and Sport, Laboratory of Applied Nutrition and Metabolism, University of São PauloAv. Prof. Mello de Moraes, 65, ButantãSão Paulo, SP 05508-030Brazil[email protected]Search for other works by this author on:
-
CHAPTER 15: Human Skeletal Muscle Carnosine and Its Function: A Focus on Homeostasis, Muscle Contractility and pHp295-312ByI. Everaert;I. EveraertDepartment of Movement and Sports Sciences, Ghent UniversityWatersportlaan 29000 GhentBelgium[email protected]Search for other works by this author on:W. DeraveW. DeraveDepartment of Movement and Sports Sciences, Ghent UniversityWatersportlaan 29000 GhentBelgium[email protected]Search for other works by this author on:
-
CHAPTER 16: Anserine as a Suppressor of Fatiguep313-324ByYoshinori TakahashiYoshinori TakahashiCentral Research Institute, Maruha Nichiro Corporation16-2, WadaiTsukubaIbaraki 300-4295Japan[email protected]Search for other works by this author on:
-
CHAPTER 17: Carnosine Promotion of Wound Healingp325-340ByI. Ansurudeen;I. AnsurudeenKarolinska Institute, Department of Molecular Medicine and Surgery, Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska University HospitalSolna, L1:00171 76 StockholmSweden[email protected]Search for other works by this author on:E. Forsberg;E. ForsbergKarolinska Institute, Department of Molecular Medicine and Surgery, Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska University HospitalSolna, L1:00171 76 StockholmSweden[email protected]Search for other works by this author on:K. BrismarK. BrismarKarolinska Institute, Department of Molecular Medicine and Surgery, Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska University HospitalSolna, L1:00171 76 StockholmSweden[email protected]Search for other works by this author on:
-
CHAPTER 18: Carnosine and Ischemia/Reperfusion Injuryp341-355ByLatif Abbasoğlu;Latif AbbasoğluDepartment of Pediatric Surgery, Acibadem University Faculty of MedicineKozyatağıIstanbulTurkey[email protected]Search for other works by this author on:Semra Doğru-Abbasoğlu;Semra Doğru-AbbasoğluDepartment of Biochemistry, Istanbul Faculty of Medicine, Istanbul UniversityÇapaIstanbulTurkeySearch for other works by this author on:Müjdat UysalMüjdat UysalDepartment of Biochemistry, Istanbul Faculty of Medicine, Istanbul UniversityÇapaIstanbulTurkeySearch for other works by this author on:
-
CHAPTER 19: Antigenotoxic Effects of Carnosinep356-371ByAhmet Güner;Ahmet GünerDepartment of Biology, Faculty of Art and Science, Fatih UniversityIstanbul 34500Turkey[email protected]Search for other works by this author on:Lokman AlpsoyLokman AlpsoyDepartment of Biology, Faculty of Art and Science, Fatih UniversityIstanbul 34500Turkey[email protected]Search for other works by this author on:
-
CHAPTER 20: Carnosine and Cancerp372-392ByFrank Gaunitz;Frank GaunitzKlinik und Poliklinik für Neurochirurgie, Universitätsklinikum Leipzig AöRLiebigstraße 2004103 LeipzigGermany[email protected]Search for other works by this author on:Henry Oppermann;Henry OppermannKlinik und Poliklinik für Neurochirurgie, Universitätsklinikum Leipzig AöRLiebigstraße 2004103 LeipzigGermany[email protected]Search for other works by this author on:Alan HipkissAlan HipkissAston Research Centre for Healthy Ageing (ARCHA), School of Health and Life Sciences, Aston UniversityBirmingham B4 7ETUKSearch for other works by this author on:
-
CHAPTER 21: l-Carnosine and Human Colon Cancerp393-411ByBarbara Iovine;Barbara IovineDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico IIVia Pansini, 580131 NapoliItaly[email protected]Search for other works by this author on:Mariangela Garofalo;Mariangela GarofaloDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico IIVia Pansini, 580131 NapoliItaly[email protected]Search for other works by this author on:Maria Orefice;Maria OreficeDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico IIVia Pansini, 580131 NapoliItaly[email protected]Search for other works by this author on:Maria Assunta BevilacquaMaria Assunta BevilacquaDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico IIVia Pansini, 580131 NapoliItaly[email protected]Search for other works by this author on:
-
CHAPTER 22: Carnosine-Induced Neuroprotectionp412-431ByS. M. Fayaz;S. M. FayazSchool of Biotechnology, Coordinator, DBT – Centre for Bioinformatics, National Institute of Technology CalicutCalicut-673601India[email protected]Search for other works by this author on:Arshad Majid;Arshad MajidSheffield Institute for Translational Neuroscience (SITraN), University of Sheffield385A Glossop RoadSheffield S10 2HQUKSearch for other works by this author on:G. K. RajanikantG. K. RajanikantSchool of Biotechnology, Coordinator, DBT – Centre for Bioinformatics, National Institute of Technology CalicutCalicut-673601India[email protected]Search for other works by this author on:
-
CHAPTER 23: Carnosine and Vascular Dementiap432-450ByJing Ma;Jing MaDepartment of Pharmacology, Key Laboratory of Medical Neurobiology of the Ministry of Health of China, Zhejiang Province Key Laboratory of Neurobiology, College of Pharmaceutical Sciences, School of Medicine, Zhejiang UniversityHangzhouZhejiang 310058P. R. China[email protected]Department of Pharmacy, Xinhua Hospital, Shanghai Jiaotong University, School of MedicineShanghai 200092ChinaSearch for other works by this author on:Zhong ChenZhong ChenDepartment of Pharmacology, Key Laboratory of Medical Neurobiology of the Ministry of Health of China, Zhejiang Province Key Laboratory of Neurobiology, College of Pharmaceutical Sciences, School of Medicine, Zhejiang UniversityHangzhouZhejiang 310058P. R. China[email protected]Search for other works by this author on:
-
CHAPTER 24: Carnosine and Alzheimer’s Disease-Related Fibril Formationp451-470ByAlessandra Aloisi;Alessandra AloisiIstituto Nanoscienze-CNR, Euromediterranean Center for Nanomaterial Modelling and Technology (ECMT), via Arnesano 73100LecceItalySearch for other works by this author on:Ross RinaldiRoss RinaldiDepartment of Mathematics and Physics ‘‘E. De Giorgi’’, Università del SalentoLecceItaly[email protected]Search for other works by this author on:
-
CHAPTER 25: The Function of Carnosine and Its Homologs on Behaviorp471-492ByMitsuhiro FuruseMitsuhiro FuruseLaboratory of Regulation in Metabolism and Behavior, Faculty of Agriculture, Kyushu UniversityFukuoka 812-8581Japan[email protected]Search for other works by this author on:
-
CHAPTER 26: Carnosine and Kidney Diseasesp493-509ByKatarzyna Kiliś-PstrusińskaKatarzyna Kiliś-PstrusińskaDepartment of Paediatric Nephrology, Wroclaw Medical UniversityUl. Borowska 21350-556 WrocławPoland[email protected]Search for other works by this author on:
-
CHAPTER 27: Carnosine Protection Against Liver Injuryp510-527ByMüjdat Uysal;Müjdat UysalDepartment of Biochemistry, Istanbul Medical Faculty, Istanbul UniversityÇapaIstanbulTurkey[email protected]Search for other works by this author on:Necla Koçak-Toker;Necla Koçak-TokerDepartment of Biochemistry, Istanbul Medical Faculty, Istanbul UniversityÇapaIstanbulTurkey[email protected]Search for other works by this author on:Semra Doğru-AbbasoğluSemra Doğru-AbbasoğluDepartment of Biochemistry, Istanbul Medical Faculty, Istanbul UniversityÇapaIstanbulTurkey[email protected]Search for other works by this author on:
-
CHAPTER 28: The Blood–Retinal Barrier and Carnosinep528-547ByYoshiyuki Kubo;Yoshiyuki KuboDepartment of Pharmaceutics, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama2630 SugitaniToyama930-0194Japan[email protected]Search for other works by this author on:Shin-Ichi Akanuma;Shin-Ichi AkanumaDepartment of Pharmaceutics, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama2630 SugitaniToyama930-0194Japan[email protected]Search for other works by this author on:Ken-Ichi HosoyaKen-Ichi HosoyaDepartment of Pharmaceutics, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama2630 SugitaniToyama930-0194Japan[email protected]Search for other works by this author on:
-
CHAPTER 29: l-Carnosine and Zinc in Gastric Protectionp548-565ByHyuk Soon Choi;Hyuk Soon ChoiDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Institute of Digestive Disease and Nutrition, Korea University College of MedicineInchon-ro 73, Seongbuk-guSeoul136-705Korea[email protected]Search for other works by this author on:Eun Sun Kim;Eun Sun KimDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Institute of Digestive Disease and Nutrition, Korea University College of MedicineInchon-ro 73, Seongbuk-guSeoul136-705Korea[email protected]Search for other works by this author on:Bora Keum;Bora KeumDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Institute of Digestive Disease and Nutrition, Korea University College of MedicineInchon-ro 73, Seongbuk-guSeoul136-705Korea[email protected]Search for other works by this author on:Hoon Jai Chun;Hoon Jai ChunDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Institute of Digestive Disease and Nutrition, Korea University College of MedicineInchon-ro 73, Seongbuk-guSeoul136-705Korea[email protected]Search for other works by this author on:Mi-Kyung SungMi-Kyung SungDepartment of Food and Nutrition, Sookmyung Women’s University100 Cheongpa-ro 47-gil, Yongsan-guSeoul140-742KoreaSearch for other works by this author on:
Spotlight
Advertisement
Advertisement
