CHAPTER 42: Function and Effects of Pyridoxine (Vitamin B₆): An Epidemiological Review of Evidence

In addition to its coenzymatic function in metabolism, vitamin B₆ has the potential effect of preventing chronic diseases such as vascular diseases and cancer. Recent evidence from observational studies indicates that vitamin B₆ status is highly likely to be associated with vascular diseases, although findings from clinical trials have been limited and inconsistent. Evidence from observational studies indicates a possible association between vitamin B₆ status and cancer, particularly colorectal cancer, although no significant protective effect of vitamin B₆ has been found in clinical trials.