CHAPTER 10: Cationic Triazine Dendrimers: Synthesis, Characterization, and Biological Applications

Triazine dendrimers—globular polymers ranging from small-molecule to viral dimensions—have lived up to the claim of “if it can be cartooned, it can be made”, as illustrated in the diversity in sizes and compositions that have been produced. While largely unexplored in applications associated with regenerative medicine, their potential as scaffolding materials and in the display of ligands or other bioactive agents suggest future opportunities. This chapter summarizes 15 years of efforts in this field with the desire to inspire new uses for this versatile class of materials. With rare and noted exceptions, triazine dendrimers are cationic.