Stem Cell-Based Tissue Repair
The need for customized stem cell therapies for specific conditions will be a major issue in the coming decades. This unique book by experts in the field reviews the subject as it stands today. Its coverage includes: basic and applied stem cell research and history; sources of adult stem cells; a comparison of difficulties in derivation, and the applications of embryonic and adult stem cells. Specific topics dealt with include advantages and problems associated with stem cell / matrix interactions and stem cell differentiation, difficulties using stem cells for clinical application, stem cell based tissue engineering - myth or reality, stem cells and immunity, natural biological matrices versus synthetic (biocompatibility and integration), stem cell delivery, labeling, imaging and tracking, bioreactors: 2D and 3D cell culturing for in-vitro studies and for stem cell implantation, ethical and safety issues and Good Manufacturing Practice (GMP).
Stem Cell-Based Tissue Repair, The Royal Society of Chemistry, 2010.
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Promises and Limitations in the Application of Cell Therapy for Tissue Regenerationp1-21ByRaphael GorodetskyRaphael GorodetskyLaboratory of Biotechnology and Radiobiology, Sharett Institute of Oncology, Hadassah Hebrew University Medical CenterJerusalemIsraelSearch for other works by this author on:
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Chapter 2: Adult Non-hematopoietic Stem Cells and Progenitor Cells (aNHSCs)p22-44ByR. Schäfer;R. SchäferHarvard Stem Cell InstituteDepartment of Stem Cell and Regenerative Biology, Harvard University7 Divinity AvenueCambridgeMA 02138USASearch for other works by this author on:L. DahéronL. DahéronHarvard Stem Cell InstituteSearch for other works by this author on:
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Chapter 3: Screening Approaches for Stem Cellsp45-80ByDavid G. Buschke;David G. BuschkeDepartment of Biomedical EngineeringLaboratory for Optical and Computational InstrumentationSearch for other works by this author on:Derek J. Hei;Derek J. HeiSchool of Medicine and Public HealthSearch for other works by this author on:Kevin W. Eliceiri;Kevin W. EliceiriDepartment of Biomedical EngineeringLaboratory for Optical and Computational InstrumentationSearch for other works by this author on:Brenda M. OgleBrenda M. OgleDepartment of Biomedical EngineeringLaboratory for Optical and Computational InstrumentationMaterial Sciences Program, University of Wisconsin at MadisonMadisonWisconsin 53706USASearch for other works by this author on:
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Chapter 4: Hematopoietic Stem Cells and their Role in Regenerative Medicinep81-88ByEitan FibachEitan FibachDepartment of Hematology, Hadassah – Hebrew University Medical CentreJerusalemIsraelSearch for other works by this author on:
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Chapter 5: Cord and Cord Blood: Valuable Resources with Potential for Liver Therapyp89-116BySaba Habibollah;Saba HabibollahInstitute of Genetics, Newcastle UniversityNewcastle-upon-TyneUKSearch for other works by this author on:Marcin Jurga;Marcin JurgaCell Therapy Research InstituteCTI-LyonLyonFranceSearch for other works by this author on:Nico Forraz;Nico ForrazCell Therapy Research InstituteCTI-LyonLyonFranceSearch for other works by this author on:Colin McGuckinColin McGuckinCell Therapy Research InstituteCTI-LyonLyonFranceSearch for other works by this author on:
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Chapter 6: Induced Pluripotent Stem Cells: Their Role in Modeling Disease and Regenerative Medicinep117-140ByYonatan Stelzer;Yonatan StelzerStem Cell Unit, Department of Genetics, Institute of Life Sciences, The Hebrew UniversityEdmund Safra Campus, Givat RamJerusalem91904IsraelSearch for other works by this author on:Marjorie PickMarjorie PickStem Cell Unit, Department of Genetics, Institute of Life Sciences, The Hebrew UniversityEdmund Safra Campus, Givat RamJerusalem91904IsraelSearch for other works by this author on:
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Chapter 7: Mesenchymal Stromal/Stem Cells from Tissue Repair to Destruction of Tumor Cellsp141-158ByRita Bussolari;Rita BussolariDepartment of OncologyHematology and Respiratory DiseasesSearch for other works by this author on:Giulia Grisendi;Giulia GrisendiDepartment of OncologyHematology and Respiratory DiseasesSearch for other works by this author on:Luigi Cafarelli;Luigi CafarelliDepartment of OncologyHematology and Respiratory DiseasesSearch for other works by this author on:Laura Scarabelli;Laura ScarabelliDepartment of OncologyHematology and Respiratory DiseasesSearch for other works by this author on:Antonio Frassoldati;Antonio FrassoldatiDepartment of OncologyHematology and Respiratory DiseasesSearch for other works by this author on:Michela Maur;Michela MaurDepartment of OncologyHematology and Respiratory DiseasesSearch for other works by this author on:Paolo Paolucci;Paolo PaolucciDepartment of Mother and Child, University-Hospital of Modena and Reggio EmiliaModenaItalySearch for other works by this author on:Pierfranco Conte;Pierfranco ConteDepartment of OncologyHematology and Respiratory DiseasesSearch for other works by this author on:Massimo DominiciMassimo DominiciDepartment of OncologyHematology and Respiratory DiseasesSearch for other works by this author on:
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Chapter 8: Fibrin-based Matrices to Support Stem Cell-Based Tissue Regenerationp159-177ByRaphael Gorodetsky;Raphael GorodetskyHadassah Hebrew University Medical CenterJerusalemIsraelSearch for other works by this author on:Iris Mironi-Harpaz;Iris Mironi-HarpazFaculty of Biomedical EngineeringTechnion-Israel Institute of TechnologyHaifaIsraelSearch for other works by this author on:Dror SeliktarDror SeliktarFaculty of Biomedical EngineeringTechnion-Israel Institute of TechnologyHaifaIsraelSearch for other works by this author on:
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Chapter 9: Culturing Non-hematopoietic Mesenchymal Stromal Cells and Requirements of GMP in Stem Cell-based Therapiesp178-202ByKaren Bieback;Karen BiebackInstitute of Transfusion Medicine and Immunology, Medical Faculty Mannheim, Heidelberg UniversityDRK-Blutspendedienst, Ludolf-Krehl-Strasse 13-17D-68167 MannheimGermanySearch for other works by this author on:Marianna Karagianni;Marianna KaragianniInstitute of Transfusion Medicine and Immunology, Medical Faculty Mannheim, Heidelberg UniversityDRK-Blutspendedienst, Ludolf-Krehl-Strasse 13-17D-68167 MannheimGermanySearch for other works by this author on:Gerlinde Schmidtke-Schrezenmeier;Gerlinde Schmidtke-SchrezenmeierInstitute of Clinical Transfusion Medicine and Immunogenetics Ulm, German Red Cross Blood Service Baden-Württemberg – Hessia and Institute of Transfusion Medicine, University of UlmUlmGermanySearch for other works by this author on:Natalie Fekete;Natalie FeketeInstitute of Clinical Transfusion Medicine and Immunogenetics Ulm, German Red Cross Blood Service Baden-Württemberg – Hessia and Institute of Transfusion Medicine, University of UlmUlmGermanySearch for other works by this author on:Hubert SchrezenmeierHubert SchrezenmeierInstitute of Clinical Transfusion Medicine and Immunogenetics Ulm, German Red Cross Blood Service Baden-Württemberg – Hessia and Institute of Transfusion Medicine, University of UlmUlmGermanySearch for other works by this author on:
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Chapter 10: (Stem) Cell Based Therapy for Neurological Disordersp203-234ByO. Einstein;O. EinsteinDepartment of Neurology, The Agnes Ginges Center for Human Neurogenetics, Hadassah–Hebrew University Medical CenterJerusalemIsraelSearch for other works by this author on:T. Ben-HurT. Ben-HurDepartment of Neurology, The Agnes Ginges Center for Human Neurogenetics, Hadassah–Hebrew University Medical CenterJerusalemIsraelSearch for other works by this author on:
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Chapter 11: Mesenchymal Osteogenic Precursors for Bone Repair and Regenerationp235-247ByNicola Baldini;Nicola BaldiniClinica Ortopedica e Traumatologica ILaboratorio di Fisiopatologia Ortopedica e Medicina Rigenerativa, Istituto Ortopedico RizzoliVia di Barbiano 1/1040136 BolognaItalySearch for other works by this author on:Dante Dallari;Dante DallariClinica Ortopedica e Traumatologica ISearch for other works by this author on:Francesca PerutFrancesca PerutLaboratorio di Fisiopatologia Ortopedica e Medicina Rigenerativa, Istituto Ortopedico RizzoliVia di Barbiano 1/1040136 BolognaItalySearch for other works by this author on:
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Chapter 12: Stem Cells and Cartilage Repairp248-272ByBernd Rolauffs;Bernd RolauffsCenter for Regenerative Biology and Medicine, University of TübingenGermanyBG Trauma Centre, University of Tübingen Medical CentreTübingenGermanySearch for other works by this author on:Andreas Badke;Andreas BadkeBG Trauma Centre, University of Tübingen Medical CentreTübingenGermanySearch for other works by this author on:Kuno Weise;Kuno WeiseBG Trauma Centre, University of Tübingen Medical CentreTübingenGermanySearch for other works by this author on:Alan J. Grodzinsky;Alan J. GrodzinskyCenter for Biomedical EngineeringMITCambridgeUSASearch for other works by this author on:Wilhelm K. AicherWilhelm K. AicherCenter for Regenerative Biology and Medicine, University of TübingenGermanyCenter for Medical Research, University of Tübingen Medical FacultyTübingenGermanySearch for other works by this author on:
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Chapter 13: Stem Cell-based Replacement Tissue for Heart Repairp273-295ByAyelet Lesman;Ayelet LesmanBio-Medical Engineering, TechnionHaifaIsraelSearch for other works by this author on:Shulamit LevenbergShulamit LevenbergBio-Medical Engineering, TechnionHaifaIsraelSearch for other works by this author on:
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Chapter 14: Regeneration of the Vascular Systemp296-307ByM. Schleicher;M. SchleicherDepartment of Thoracic and Cardiovascular Surgery, University Hospital TübingenTübingenGermanySearch for other works by this author on:A. J. Huber;A. J. HuberDepartment of Thoracic and Cardiovascular Surgery, University Hospital TübingenTübingenGermanySearch for other works by this author on:H. P. Wendel;H. P. WendelSurgery of Congenital Heart Defects And Pediatric Cardio-surgery, Children's University Hospital TübingenTübingenGermanySearch for other works by this author on:U. A. StockU. A. StockDepartment of Thoracic and Cardiovascular Surgery, University Hospital TübingenTübingenGermanySearch for other works by this author on:
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Chapter 15: Regenerative Strategies for the Endocrine Pancreas: From Islets to Stem Cells and Tissue Reprogrammingp308-323ByJuan Domínguez-Bendala;Juan Domínguez-BendalaDiabetes Research Institute, University of Miami1450 NW 10th AvenueMiamiFL 33136USASearch for other works by this author on:Camillo RicordiCamillo RicordiDiabetes Research Institute, University of Miami1450 NW 10th AvenueMiamiFL 33136USASearch for other works by this author on:
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Chapter 16: Regeneration of the Lower Urinary Tract: Clinical Applications and Future Outlookp324-345ByMarkus Renninger;Markus RenningerDepartment of UrologyUniversity of TuebingenGermanySearch for other works by this author on:Bastian Amend;Bastian AmendDepartment of UrologyUniversity of TuebingenGermanySearch for other works by this author on:Jörg Seibold;Jörg SeiboldDepartment of UrologyUniversity of TuebingenGermanySearch for other works by this author on:Gerhard Feil;Gerhard FeilDepartment of UrologyUniversity of TuebingenGermanySearch for other works by this author on:Arnulf Stenzl;Arnulf StenzlDepartment of UrologyUniversity of TuebingenGermanySearch for other works by this author on:Karl-Dietrich SievertKarl-Dietrich SievertDepartment of UrologyUniversity of TuebingenGermanySearch for other works by this author on:
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Chapter 17: Effective Tissue Repair and Immunomodulation by Mesenchymal Stem Cells within a Milieu of Cytokinesp346-365ByPhilip Lim;Philip LimNew Jersey Medical School-UMDNJ, Department of Medicine, Division of Hematology/OncologyNewark, NJUSASearch for other works by this author on:Shyam A. Patel;Shyam A. PatelNew Jersey Medical School-UMDNJ, Department of Medicine, Division of Hematology/OncologyNewark, NJUSAGraduate School of Biomedical Sciences-UMDNJNewark, NJUSASearch for other works by this author on:Pranela RameshwarPranela RameshwarNew Jersey Medical School-UMDNJ, Department of Medicine, Division of Hematology/OncologyNewark, NJUSASearch for other works by this author on:
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Chapter 18: Homing of Mesenchymal Stromal Cellsp366-377ByReinhard Henschler;Reinhard HenschlerDRK Institute of Transfusion Medicine and Immune Hematology, Sandhofstrasse 1, 60528FrankfurtGermanySearch for other works by this author on:Erika Deak;Erika DeakDRK Institute of Transfusion Medicine and Immune Hematology, Sandhofstrasse 1, 60528FrankfurtGermanySearch for other works by this author on:Richard SchäferRichard SchäferHarvard Stem Cell Institute, Harvard University7 Divinity AvenueCambridgeMA 02138USADepartment of Stem Cell and Regenerative Biology, Harvard University7 Divinity AvenueCambridgeMA 02138USASearch for other works by this author on:
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