Stem Cell-Based Tissue Repair
Chapter 2: Adult Non-hematopoietic Stem Cells and Progenitor Cells (aNHSCs)
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Published:03 Dec 2010
R. Schäfer and L. Dahéron, in Stem Cell-Based Tissue Repair, ed. R. Gorodetsky and R. Schäfer, The Royal Society of Chemistry, 2010, ch. 2, pp. 22-44.
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Stem cells are primitive cells which are capable of self renewal and differentiation into more specialized cells. Although this property is shared, each stem cell has a unique set of cells they can differentiate into. Therefore, the molecular signature or “stemness” might be distinctive for each stem cell type, reflecting their unique potential. This chapter gives an overview on general issues of stem cells focusing on differentiation and the stem cell niche. Moreover, distinct types of adult non-hematopoietic stem cells featuring promising potential in the field of cellular therapies and tissue engineering will be characterized.
