Unravelling Single Cell Genomics
Chapter 2: The Central Dogma in Molecular Biology
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Published:18 Oct 2010
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Special Collection: 2010 ebook collection , 2010 ebook collection , 2010 materials and nanoscience subject collectionSeries: Nanoscience & Nanotechnology
Laili Mahmoudian, 2010. "The Central Dogma in Molecular Biology", Unravelling Single Cell Genomics, Jean-Christophe Baret, Bruno Cauli, Max Chabert, Valerie Abecassis-Taly, Petra Dittrich, Emmanuel Fort, Christoph Klein, Joel Lachuer, Bertrand Lambolez, Nicholas Le Novere, Severine le Gac, Laili Mahmoudian, Yann Marcy, Bernhard Polzer, Joelle Vinh, Tania Vitalis, Nathalie Bontoux, Marie-Claude Potier, Luce Dauphinot, Harold Craighead, Harry Kroto, Paul O'Brien, Royal Society of Chemistry
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The central dogma tells that the genetic information coded by DNA molecules, first transferred to RNA molecules as intermediated molecules, is then transferred to protein molecules. In other words it says that the genetic information is saved as sequences of nucleic acids but the function has to be expressed in the form of proteins. There are three steps in the conversion of the genetic information to the proteins: replication, transcription and translation. Figure 2.1 shows the principals of central dogma.
