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Nanoscience & Nanotechnology Series
Unravelling Single Cell Genomics
By
Severine le Gac;
Severine le Gac
University of Twente, Netherlands
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Royal Society of Chemistry
Royal Society of Chemistry
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Edited by
Nathalie Bontoux;
Nathalie Bontoux
Agilent Technologies, France
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Harold Craighead;
Harold Craighead
Cornell University, USA
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Paul O'Brien
Paul O'Brien
University of Manchester, UK
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Hardback ISBN:
978-1-84755-911-1
PDF ISBN:
978-1-84973-228-4
Special Collection:
2010 ebook collection
,
2010 ebook collection
,
2000-2010 materials and nanoscience subject collection
,
2010 materials and nanoscience subject collection
Series:
Nanoscience & Nanotechnology
No. of Pages:
336
Publication date:
18 Oct 2010
Book Chapter
Chapter 2: The Central Dogma in Molecular Biology
By
Laili Mahmoudian
Laili Mahmoudian
CRICM, UPMC – INSERM URMS975 – CNRS UMR7225, Hôpital de la Pitié Salpétrière
Paris
France
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-
Published:18 Oct 2010
Page range:
15 - 25
Citation
L. Mahmoudian, in Unravelling Single Cell Genomics, ed. N. Bontoux, M. Potier, L. Dauphinot, H. Craighead, H. Kroto, and P. O'Brien, The Royal Society of Chemistry, 2010, ch. 2, pp. 15-25.
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The central dogma tells that the genetic information coded by DNA molecules, first transferred to RNA molecules as intermediated molecules, is then transferred to protein molecules. In other words it says that the genetic information is saved as sequences of nucleic acids but the function has to be expressed in the form of proteins. There are three steps in the conversion of the genetic information to the proteins: replication, transcription and translation. Figure 2.1 shows the principals of central dogma.
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