Skip to Main Content
Skip Nav Destination

Parkinson's disease (PD) is a chronic neurodegenerative disease that involves the selective loss of dopaminergic neuronal cells in the substantia nigra (SN) in the midbrain. The studies in PD-affected individuals as well as animal, cellular and toxicant-based disease models have provided information about the mechanisms involved in PD etiology. Intracellular signaling pathways offer a mechanistic explanation for how an initial event may induce selective cell death in PD and also specific targets for therapeutic intervention in PD.

This content is only available via PDF.
You do not currently have access to this chapter, but see below options to check access via your institution or sign in to purchase.
Don't already have an account? Register
Close Modal

or Create an Account

Close Modal
Close Modal