Chapter 11: Anionic oligosaccharides: synthesis and applications
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Published:20 Mar 2014
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E. Grand, J. Kovensky, G. Pourceau, S. Toumieux, and A. Wadouachi, in Carbohydrate Chemistry: Chemical and Biological Approaches, Volume 40, ed. A. Pilar Rauter, T. Lindhorst, and Y. Queneau, The Royal Society of Chemistry, 2014, vol. 40, ch. 11, pp. 195-235.
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Anionic oligosaccharides are largely involved in physiological and pathological processes. The controlled production of these biomolecules is crucial for the comprehension of the biological mechanisms in which they are involved, but it is still challenging and troublesome. This chapter reviews the recent protocols (since 2008) described in literature for the obtaining of anionic oligosaccharides by de novo synthesis and by polysaccharide depolymerisation. An overview on recent applications is also presented.
