Carbohydrate Chemistry: Chemical and Biological Approaches, Volume 40
Chapter 19: How recent knowledge on furano-specific enzymes has renewed interest for the synthesis of glycofuranosyl-containing conjugates
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Published:20 Mar 2014
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Vincent Ferrières, Caroline Nugier-Chauvin, Laurent Legentil, Sylvain Tranchimand, 2014. "How recent knowledge on furano-specific enzymes has renewed interest for the synthesis of glycofuranosyl-containing conjugates", Carbohydrate Chemistry: Chemical and Biological Approaches, Volume 40, Amelia Pilar Rauter, Thisbe Lindhorst, Yves Queneau
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Sweden Academy of Sciences awarded E. Fischer in 1902 for his prediction of parentage of carbohydrates, the stereochemical elucidation of these highly stereogenic simple blocks, and, very importantly too, for their striking ability to adopt several forms, so that sugars can be drawn either linearly or as a five- (furanose) or a six-membered (pyranose) ring. To this major discovery in the field of natural molecules followed many efforts in analytical approaches, chemical modifications and synthesis. However, because mammals are able to biosynthesize only pyranosyl-containing conjugates and polymers, with the exception of nucleic acids, the scientific community was mainly attracted by...