Singlet Oxygen: Applications in Biosciences and Nanosciences
Chapter 8: Activatable Photosensitizers
Published:27 Jan 2016
Special Collection: 2016 ebook collection
R. Bresolí-Obach, C. Hally, and S. Nonell, in Singlet Oxygen: Applications in Biosciences and Nanosciences, ed. S. Nonell, C. Flors, S. Nonell, and C. Flors, The Royal Society of Chemistry, 2016, ch. 8, pp. 163-181.
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The controlled generation of singlet oxygen is of great interest owing to its potential. The specificity of 1O2 generation is controlled by three factors: light, O2 and a photosensitizer. Yet, nowadays some applications still require even further specificity. A possible solution is to introduce a fourth factor that can establish a control mechanism by means of an external stimuli. In this chapter, the main activation mechanisms of photosensitizers will be covered: self-quenching, energy and electron transfer and 1O2 scavengers. Some external stimuli are necessary to activate this fourth factor. Examples of these are: molecular recognition, enzymes, pH, small molecules, light activation, viscosity and even a combination of them.