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SPR Organometallic Chemistry
Organometallic Chemistry: Volume 43
Edited by
Nathan J Patmore;
Nathan J Patmore
University of Huddersfield, UK
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Paul I P Elliott
Paul I P Elliott
University of Huddersfield, UK
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Volume
43
Hardback ISBN:
978-1-78801-691-9
PDF ISBN:
978-1-78801-707-7
EPUB ISBN:
978-1-78801-708-4
Special Collection:
2020 ebook collection
No. of Pages:
228
Published online:
02 Nov 2020
Published in print:
09 Nov 2020
Book Chapter
Organometallic compounds of ruthenium and their application in chemotherapy
By
Wen-Jie Mei
;
Wen-Jie Mei
Guangdong Province Engineering Technology Centre for Molecular Probe & Biomedicine Imaging
Guangzhou
510006
China
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Qiong Wu
;
Qiong Wu
Guangdong Province Engineering Technology Centre for Molecular Probe & Biomedicine Imaging
Guangzhou
510006
China
Integrated Chinese and Western Medicine Postdoctoral Research Station, Jinan University
Guangzhou
510632
China
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Wen-Hui Peng
;
Wen-Hui Peng
The Public Health Department, Guangdong Pharmaceutical University
Guangzhou
510006
China
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Jing Shu
Jing Shu
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-
Published:02 Nov 2020
-
Special Collection: 2020 ebook collection
Page range:
35 - 62
Citation
W. Mei, Q. Wu, J. Qian, W. Peng, and J. Shu, in Organometallic Chemistry: Volume 43, ed. N. J. Patmore and P. I. P. Elliott, The Royal Society of Chemistry, 2020, vol. 43, pp. 35-62.
Download citation file:
Arene ruthenium(ii) complexes as potential inhibitors in chemotherapy have been reviewed. It is revealed that arene ruthenium(ii) complexes coordinated with varied ligands exhibit promising inhibitory activity against the proliferation, migration and invasion. It is also shown that this kind of complexes exert their antitumor activity through inducing apoptosis, cell cycle arrest and/or DNA damage of tumor cells.
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