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The concepts of catalysis and surface science are introduced, and several promising aspects of surface science studies related to heterogeneous catalysis are presented, mixed with some personal understanding. Emphasis is given to the microscopic view on catalytic reactions, structural and electronic requirement of a catalyst, the surface science approach to explore mechanism of heterogeneous catalytic reactions occurring on surface, subsurface and supported metal nanoparticles, and the development of operando surface science techniques.

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