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This chapter highlights several useful characteristics and mechanical properties of CBs and bambusurils (BUs), which may offer interesting opportunities in the design and synthesis of machines, switches and cargo delivery devices. Three selected CB-based tools and applications are discussed: (a) molecular rotary motors that involve shuttling of CBs along polyaminated threads, CB-based high-speed rotary motors and exploration of new binding mechanisms; (b) sensory devices that detect and quantify specific analytes via single or multiple-binding events, as well as switch devices that comprise bistable rotaxanes; and (c) utilization of CBs for controlled cargo delivery and release, as well as the use of hetero-bambusurils for multiple anion binding, channeling and ion transport. One can easily predict that these fascinating families of host molecules will be applied in the foreseeable future in drug delivery, targeting and release, diagnostics and analytical chemistry, as well as new materials, including advanced macromolecules, functional nanocapsules, and innovative supramolecular architecture.

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