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SPR Carbohydrate Chemistry
Carbohydrate Chemistry: Chemical and Biological Approaches, Volume 45
Edited by
Amélia Pilar Rauter;
Amélia Pilar Rauter
Universidade de Lisboa, Portugal
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Thisbe K Lindhorst;
Thisbe K Lindhorst
Kiel University, Germany
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Yves Queneau
Yves Queneau
INSA Lyon, France
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Volume
45
Hardback ISBN:
978-1-83916-390-6
PDF ISBN:
978-1-83916-453-8
EPUB ISBN:
978-1-83916-454-5
Special Collection:
2021 ebook collection
No. of Pages:
664
Published online:
15 Dec 2021
Published in print:
22 Dec 2021
Book Chapter
Cyclopeptides as glycan-presenting multivalent scaffolds
By
David Goyard
;
David Goyard
Département de Chimie Moléculaire, Université Grenoble Alpes
UMR 5250, CNRS
38000 Grenoble
France
[email protected]
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Olivier Renaudet
Olivier Renaudet
Département de Chimie Moléculaire, Université Grenoble Alpes
UMR 5250, CNRS
38000 Grenoble
France
[email protected]
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-
Published:15 Dec 2021
-
Special Collection: 2021 ebook collection
Page range:
499 - 518
Citation
D. Goyard and O. Renaudet, in Carbohydrate Chemistry: Chemical and Biological Approaches, Volume 45, ed. A. Pilar Rauter, T. K. Lindhorst, and Y. Queneau, The Royal Society of Chemistry, 2021, vol. 45, pp. 499-518.
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This chapter highlights recent advances in the utilization of cyclopeptides as scaffolds for the construction of homo- and heterovalent glycoclusters and glycodendrimers. The structural modularity of cyclopeptides is demonstrated through selected examples showing different sugar valency, variations in the scaffold geometry and the molecular composition. Biological interest of these structures as bacterial or viral lectin ligands and antitumoral synthetic vaccines are particularly described.
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