Metal-Carbon Bonds in Enzymes and Cofactors
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The occurrence of a wide variety of metal-carbon bonds in living organisms, ranging from bacteria to humans, is only recently recognized. Of course, the historical examples are the B12 coenzymes containing cobalt-carbon bonds, but now such bonds are also known for nickel, iron, copper, and other transition metal ions. There is no other comparable book; MILS-6, written by 17 experts, summarizes the most recent insights into this fascinating topic.
B. Kraeutler, R. G. Matthews, R. K. Thauer, P. A. Lindahl, J. C. F. Camps, J. W. Peters, ... R. Hille, Metal-Carbon Bonds in Enzymes and Cofactors, The Royal Society of Chemistry, 2009.
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Table of contents
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1: Organometallic Chemistry of B12 Coenzymesp1-51ByBernhard KräutlerBernhard KräutlerInstitute of Organic Chemistry and Centre of Molecular Biosciences, University of InnsbruckA-6020InnsbruckAustria[email protected]Search for other works by this author on:
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2: Cobalamin- and Corrinoid-Dependent Enzymesp53-114ByRowena G. MatthewsRowena G. MatthewsDepartment of Biological Chemistry and Life Sciences Institute, University of MichiganAnn ArborMI 48109-2216USA[email protected]Search for other works by this author on:
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3: Nickel-Alkyl Bond Formation in the Active Site of Methyl-Coenzyme M Reductasep115-132ByRudolf K. ThauerRudolf K. ThauerMax Planck Institute for Terrestrial MicrobiologyKarl-von-Frisch-StrasseD-35043 MarburgGermany[email protected]Search for other works by this author on:
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4: Nickel-Carbon Bonds in Acetyl-Coenzyme A Synthases/Carbon Monoxide Dehydrogenasesp133-150ByPaul A. LindahlPaul A. LindahlDepartments of Chemistry and of Biochemistry and Biophysics, Texas A&M UniversityCollege Station, TX77843USA[email protected]Search for other works by this author on:
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5: Structure and Function of [NiFe]-Hydrogenasesp151-178ByJuan C. Fontecilla-CampsJuan C. Fontecilla-CampsLaboratoire de Cristallographie et de Cristallogenèse des Proteines, Institut de Biologie Structurale J. P. Ebel (CEA-CNRS-UJF)41 rue Jules HorowitzF-38027 Grenoble Cédex 1France[email protected]Search for other works by this author on:
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6: Carbon Monoxide and Cyanide Ligands in the Active Site of [FeFe]-Hydrogenasesp179-218ByJohn W. PetersJohn W. PetersMontana State University, Department of Chemistry and Biochemistry and the Astrobiology Biogeocatalysis Research CenterBozeman, MT59717USA[email protected]Search for other works by this author on:
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7: Carbon Monoxide as Intrinsic Ligand to Iron in the Active Site of [Fe]-Hydrogenasep219-240BySeigo Shima;Seigo ShimaMax Planck Institute for Terrestrial MicrobiologyKarl-von-Frisch-StrasseD-35043 MarburgGermany[email protected]Search for other works by this author on:Rudolf K. Thauer;Rudolf K. ThauerMax Planck Institute for Terrestrial MicrobiologyKarl-von-Frisch-StrasseD-35043 MarburgGermany[email protected]Search for other works by this author on:Ulrich ErmlerUlrich ErmlerMax Planck Institute for BiophysicsMax-von-Laue-Strasse 3D-60438 Frankfurt/MainGermanySearch for other works by this author on:
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8: The Dual Role of Heme as Cofactor and Substrate in the Biosynthesis of Carbon Monoxidep241-293ByMario Rivera;Mario RiveraRalph N. Adams Institute for Bioanalytical Chemistry, Department of Chemistry, University of KansasMultidisciplinary Research Building, 2030 Becker Dr.LawrenceKS 66047USA[email protected][email protected]Search for other works by this author on:Juan C. RodríguezJuan C. RodríguezRalph N. Adams Institute for Bioanalytical Chemistry, Department of Chemistry, University of KansasMultidisciplinary Research Building, 2030 Becker Dr.LawrenceKS 66047USA[email protected][email protected]Search for other works by this author on:
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9: Copper-Carbon Bonds in Mechanistic and Structural Probing of Proteins as well as in Situations where Copper is a Catalytic or Receptor Sitep295-361ByHeather R. Lucas;Heather R. LucasDepartment of Chemistry, The Johns Hopkins University3400 N. Charles StreetBaltimoreMD 21218USA[email protected][email protected]Search for other works by this author on:Kenneth D. KarlinKenneth D. KarlinDepartment of Chemistry, The Johns Hopkins University3400 N. Charles StreetBaltimoreMD 21218USA[email protected][email protected]Search for other works by this author on:
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10: Interaction of Cyanide with Enzymes Containing Vanadium, Manganese, Non-Heme Iron, and Zincp363-393ByMartha E. Sosa-Torres;Martha E. Sosa-TorresFacultad de Química, Universidad Nacional Autónoma de México, Ciudad UniversitariaCoyoacán, 04510, D.F. MéxicoMéxico[email protected]Search for other works by this author on:Peter M. H. KroneckPeter M. H. KroneckSearch for other works by this author on:
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11: The Reaction Mechanism of the Molybdenum Hydroxylase Xanthine Oxidoreductase: Evidence Against the Formation of Intermediates Having Metal-Carbon Bondsp395-416ByRuss HilleRuss HilleSearch for other works by this author on:
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12: Computational Studies of Bioorganometallic Enzymes and Cofactorsp417-460ByThomas C. Brunold*Thomas C. Brunold*Search for other works by this author on:
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