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Genomics and Clinical Diagnostics
Edited by
David Whitehouse;
David Whitehouse
University of Hertfordshire, UK
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Ralph Rapley
Ralph Rapley
University of Hertfordshire, UK
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Hardback ISBN:
978-1-78262-821-7
EPUB ISBN:
978-1-78801-680-3
PDF ISBN:
978-1-83916-884-0
Special Collection:
RSC eTextbook Collection
Product Type:
Textbooks
No. of Pages:
574
Publication date:
29 Jan 2019
Book Chapter
16: Next-Generation Molecular Markers: Challenges, Applications and Future Perspectives†
By
Mukesh Verma
;
Mukesh Verma
Epidemiology and Genomics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute (NCI), National Institutes of Health (NIH), 9609 Medical Center Drive
Rockville
MD 20850
USA
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Debmalya Barh
;
Debmalya Barh
Centre for Genomics and Applied Gene Technology, Institute of Integrative Omics and Applied Biotechnology (IIOAB)
Nonakuri, Purba Medinipur
West Bengal-721172
India
[email protected]
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Syed Shah Hassan
Syed Shah Hassan
Departamento de Biologia Geral, Instituto de Ciências Biológicas (ICB), Universidade Federal de Minas Gerais
Pampulha
Belo Horizonte
Minas Gerais
Brazil
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Published:29 Jan 2019
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Special Collection: RSC eTextbook CollectionProduct Type: Textbooks
Page range:
494 - 530
Citation
M. Verma, D. Barh, and S. S. Hassan, in Genomics and Clinical Diagnostics, ed. D. Whitehouse and R. Rapley, The Royal Society of Chemistry, 2019, pp. 494-530.
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In this chapter we discuss the challenges in cancer biomarkers discovery. Furthermore, we discuss next-generation molecular markers and their applications in diagnostic screening, early diagnosis, risk assessment, prognosis and pharmacogenomics of immune diseases, cardiovascular diseases, metabolomic diseases, infectious diseases, neurological diseases and cancers. Additionally, we give brief accounts of therapeutic biomarkers for these selected diseases. Finally, we conclude the chapter with a future perspective on molecular biomarkers.
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