DNA Photodamage: From Light Absorption to Cellular Responses and Skin Cancer
Induction of DNA damage by sunlight is a major deleterious event in living organisms. Recent developments have dramatically improved our understanding of the photochemical processes involved at the sub-picosecond time scale and along with next generation sequencing and data processing has generated a need for a complete up-to-date coverage of the field. Written in an accessible and comprehensive manner, DNA Photodamage will appeal to all scientists working in the area whether specialists in the discipline or not and provides a complete coverage of the field, from ultrafast spectroscopy to biomedical research. Bridging the gap between photophysical and photochemical research on model systems, and in vivo and in vitro biological studies, this book aims to identify the most important research trends in the field and review their major findings.
DNA Photodamage: From Light Absorption to Cellular Responses and Skin Cancer, The Royal Society of Chemistry, 2021.
Download citation file:
Digital access
Print format
Table of contents
-
Photoinduced Processes in DNA: Basic Theoretical and Experimental Featuresp1-16ByRoberto Improta;Roberto ImprotaCNR – Consiglio Nazionale delle Ricerche, Istituto di Biostrutture e Bioimmagini (IBB-CNR)via Mezzocannone 16Italyrobimp@unina.itSearch for other works by this author on:Thierry DoukiThierry DoukiSearch for other works by this author on:
-
CHAPTER 2: Photoinduced Dimerization in DNA: Singlet Excited State Reaction Pathsp17-36ByLara Martinez-Fernandez;Lara Martinez-FernandezDepartamento de Química, Facultad de Ciencias and Institute for Advanced Research in Chemistry (IADCHEM), Universidad Autónoma de Madrid, Campus de Excelencia UAM-CSIC28049 MadridSpainSearch for other works by this author on:Roberto ImprotaRoberto ImprotaCNR – Consiglio Nazionale delle Ricerche, Istituto di Biostrutture e Bioimmagini (IBB-CNR)via Mezzocannone 16I-80136 NapoliItalyrobimp@unina.itSearch for other works by this author on:
-
CHAPTER 3: DNA Photoionization: From High to Low Energiesp37-54ByD. MarkovitsiD. MarkovitsiSearch for other works by this author on:
-
CHAPTER 4: Triplet Channel Photochemistry in DNAp55-76ByM. A. Miranda;M. A. MirandaInstituto Universitario Mixto de Tecnología Química UPV-CSIC, Universitat Politècnica de València, Consejo Superior de Investigaciones CientíficasAvda de los Naranjos s/n46022 ValenciaSpainlvirgini@itq.upv.esSearch for other works by this author on:V. Lhiaubet-ValletV. Lhiaubet-ValletInstituto Universitario Mixto de Tecnología Química UPV-CSIC, Universitat Politècnica de València, Consejo Superior de Investigaciones CientíficasAvda de los Naranjos s/n46022 ValenciaSpainlvirgini@itq.upv.esSearch for other works by this author on:
-
CHAPTER 5: Tracking Excited Electronic States in DNA From Formation to Deactivationp77-104ByAlex Hanes;Alex HanesDepartment of Chemistry and Biochemistry, The Ohio State University100 West 18th AvenueColumbusOhio 43210USAkohler.40@osu.eduSearch for other works by this author on:Yuyuan Zhang;Yuyuan ZhangDepartment of Chemistry and Biochemistry, The Ohio State University100 West 18th AvenueColumbusOhio 43210USAkohler.40@osu.eduSearch for other works by this author on:Bern KohlerBern KohlerDepartment of Chemistry and Biochemistry, The Ohio State University100 West 18th AvenueColumbusOhio 43210USAkohler.40@osu.eduSearch for other works by this author on:
-
CHAPTER 6: Influence of DNA Structure on Lesion Formation and Repair: Role of Modelling and Simulationsp105-132ByNatacha Gillet;Natacha GilletUniversité de Lyon, ENS de Lyon, CNRS UMR 5182, Laboratoire de ChimieF69342LyonFrancenatacha.gillet@ens-lyon.frSearch for other works by this author on:Emmanuelle Bignon;Emmanuelle BignonUniversité de Lorraine and CNRSLPCT UMR 7019F-54000 NancyFranceEmmanuelle.bignon@univ-lorraine.frAntonio.monari@univ-lorraine.frSearch for other works by this author on:Elise Dumont;Elise DumontUniversité de Lyon, ENS de Lyon, CNRS UMR 5182, Laboratoire de ChimieF69342LyonFrancenatacha.gillet@ens-lyon.frSearch for other works by this author on:Antonio MonariAntonio MonariUniversité de Lorraine and CNRSLPCT UMR 7019F-54000 NancyFranceEmmanuelle.bignon@univ-lorraine.frAntonio.monari@univ-lorraine.frUniversité de Paris and CNRSITODYSF-75006ParisFranceSearch for other works by this author on:
-
CHAPTER 7: Ultraviolet-induced Formation of DNA Damage in Cells and their Mutational Consequencesp133-163ByS. AdarS. AdarDepartment of Microbiology and Molecular Genetics, The Institute for Medical Research Israel–Canada, The Faculty of Medicine, The Hebrew University of JerusalemEin KeremJerusalem91120Israelsheeraa@ekmd.huji.ac.ilSearch for other works by this author on:
-
CHAPTER 8: Deamination of C-containing Cyclobutane Pyrimidine Dimers and Its Role in C to T and CC to TT Signature Mutations Caused by UV Lightp164-196ByJohn-Stephen TaylorJohn-Stephen TaylorDepartment of Chemistry, Washington University, One Brookings DriveSt. LouisMO 63130USAtaylor@wustl.eduSearch for other works by this author on:
-
CHAPTER 9: Photochemistry of RNA, RNA Monomers, and Plausible Prebiotic Precursorsp197-226BySean J. Hoehn;Sean J. HoehnDepartment of Chemistry, Case Western Reserve UniversityClevelandOhioUSA 44106carlos.crespo@case.eduSearch for other works by this author on:Naishka E. Caldero-Rodríguez;Naishka E. Caldero-RodríguezDepartment of Chemistry, Case Western Reserve UniversityClevelandOhioUSA 44106carlos.crespo@case.eduSearch for other works by this author on:Carlos E. Crespo-HernándezCarlos E. Crespo-HernándezDepartment of Chemistry, Case Western Reserve UniversityClevelandOhioUSA 44106carlos.crespo@case.eduSearch for other works by this author on:
-
CHAPTER 10: Photodamage in Mitochondriap227-251ByWil J. Reynolds;Wil J. ReynoldsDermatological Sciences, Translational and Clinical Research Institute, Newcastle University Medical SchoolNewcastle upon TyneNE2 4HHUKSearch for other works by this author on:Mark A. Birch-Machin;Mark A. Birch-MachinDermatological Sciences, Translational and Clinical Research Institute, Newcastle University Medical SchoolNewcastle upon TyneNE2 4HHUKDermatological Sciences, Translational and Clinical Research Institute, Newcastle University Medical School, The UK National Innovation Centre for AgeingNewcastle upon TyneUKmark.birch-machin@newcastle.ac.ukSearch for other works by this author on:Catherine A. BonnCatherine A. BonnDermatological Sciences, Translational and Clinical Research Institute, Newcastle University Medical SchoolNewcastle upon TyneNE2 4HHUKSearch for other works by this author on:
-
CHAPTER 11: The Role of Chromatin and Chromatin-modifying Enzymes in Regulating Nucleotide Excision Repairp252-270ByJohn J. WyrickJohn J. WyrickCenter for Reproductive Biology, Washington State UniversityPullmanWA99164USASearch for other works by this author on:
-
CHAPTER 12: Repair of UV-induced DNA Damage and RNA: A Helpful Interplay for Genome Surveillancep271-290ByJean MolinierJean MolinierInstitut de biologie moléculaire des plantes du CNRS12 rue du Général Zimmer67000 StrasbourgFrancejean.molinier@ibmp-cnrs.unistra.frSearch for other works by this author on:
-
CHAPTER 13: Role of Cyclobutane Pyrimidine Dimers in Non-genetic Related Responses in Skinp291-306ByK. P. LawrenceK. P. LawrenceSearch for other works by this author on:
-
CHAPTER 14: How do Translesion Polymerases Deal With Photodamage?p307-338ByNatália Cestari Moreno;Natália Cestari MorenoDepartment of Microbiology, Institute of Biomedical Sciences, University of Sao PauloSao PauloSPBrazilcfmmenck@usp.brDepartment of Biochemistry, Institute of Chemistry, University of Sao PauloSao PauloSPBrazilSearch for other works by this author on:Marcela Teatin Latancia;Marcela Teatin LatanciaDepartment of Microbiology, Institute of Biomedical Sciences, University of Sao PauloSao PauloSPBrazilcfmmenck@usp.brSearch for other works by this author on:Andressa Peres de Oliveira;Andressa Peres de OliveiraFaculty of Pharmaceutical Science, University of CampinasCampinasSPBrazilSearch for other works by this author on:Eduardo Padilha;Eduardo PadilhaDepartment of Microbiology, Institute of Biomedical Sciences, University of Sao PauloSao PauloSPBrazilcfmmenck@usp.brSearch for other works by this author on:Davi Jardim Martins;Davi Jardim MartinsDepartment of Microbiology, Institute of Biomedical Sciences, University of Sao PauloSao PauloSPBrazilcfmmenck@usp.brSearch for other works by this author on:Veridiana Munford;Veridiana MunfordDepartment of Microbiology, Institute of Biomedical Sciences, University of Sao PauloSao PauloSPBrazilcfmmenck@usp.brSearch for other works by this author on:Carlos Frederico Martins MenckCarlos Frederico Martins MenckDepartment of Microbiology, Institute of Biomedical Sciences, University of Sao PauloSao PauloSPBrazilcfmmenck@usp.brSearch for other works by this author on:
Spotlight
Advertisement
Advertisement