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Issues in Toxicology
Mammalian Toxicology of Insecticides
Edited by
Tim Marrs
Tim Marrs
Edentox Associates, UK
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Hardback ISBN:
978-1-84973-191-1
PDF ISBN:
978-1-84973-300-7
Series:
Issues in Toxicology
No. of Pages:
506
Publication date:
19 Jan 2012
Book Chapter
Chapter 7: Insecticides that Interfere with Insect Growth and Development
By
Timothy C Marrs
Timothy C Marrs
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Published:19 Jan 2012
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Series: Issues in Toxicology
Page range:
221 - 253
Citation
T. C. Marrs, in Mammalian Toxicology of Insecticides, ed. T. Marrs, The Royal Society of Chemistry, 2012, ch. 7, pp. 221-253.
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The insecticides discussed in this chapter target structures and physiological systems unique to insects and similar creatures and are consequently of low mammalian toxicity. This is despite one group, the ecdysone agonists, targeting an insect steroid hormonal system. Curiously, a remarkably large number of these compounds, notwithstanding their structural diversity, have adverse effects on the mammalian haematological system. As these compounds target insect development, they are not ‘knock-down’ insecticides and are not very effective against established adult insect infestation.
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