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Nuclear Analytical Techniques for Metallomics and Metalloproteomics
Edited by
Chunying Chen;
Chunying Chen
National Center for Nanoscience and Technology, China
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Zhifang Chai;
Zhifang Chai
Chinese Academy of Sciences, China
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Yuxi Gao
Yuxi Gao
Chinese Academy of Sciences, China
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Hardback ISBN:
978-1-84755-901-2
PDF ISBN:
978-1-84755-991-3
No. of Pages:
428
Publication date:
03 Jun 2010
Book Chapter
Chapter 9: Nuclear-based Metallomics in Metal-based Drugs
By
Ruiguang Ge
;
Ruiguang Ge
Department of Chemistry and Open Laboratory of Chemical Biology
The University of Hong Kong
Hong Kong, P. R.
China
The Laboratory of Integrative Biology
College of Life Sciences
Sun Yat-Sen University
Guangzhou 510006, P. R.
China
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Ivan K. Chu
;
Ivan K. Chu
Department of Chemistry and Open Laboratory of Chemical Biology
The University of Hong Kong
Hong Kong, P. R.
China
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Hongzhe Sun
Hongzhe Sun
Department of Chemistry and Open Laboratory of Chemical Biology
The University of Hong Kong
Hong Kong, P. R.
China
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-
Published:03 Jun 2010
Page range:
265 - 298
Citation
R. Ge, I. K. Chu, and H. Sun, in Nuclear Analytical Techniques for Metallomics and Metalloproteomics, ed. C. Chen, Z. Chai, and Y. Gao, The Royal Society of Chemistry, 2010, ch. 9, pp. 265-298.
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This chapter will deal with the application of advanced nuclear analytical techniques in the metallodrug research, with a focus on the metabolism and metallodrug-biomolecule interactions for the most commonly studied platinum(II)- and ruthenium(III)-containing anticancer drugs.
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