Aging and Vulnerability to Environmental Chemicals: Age-related Disorders and their Origins in Environmental Exposures
The world's aging populations, with age-related disorders affecting every organ system, are generating medical care costs rising at an unsustainable rate. Although such disorders are expected, we are now beginning to ask whether exposures to toxic environmental chemicals hasten or account for their onset. This book provides a detailed review of current knowledge about the possible associations between a variety of chemical contaminants and adverse effects later in life. It will serve as a guide to policy decisions about protecting us from chemical exposures that distort the aging process. It provides a guide to current understanding of how our contaminated environment may be influencing the aging process and contains examples of approaches that will help us undertake further research on this topic. It will help alert policy makers to the implications of chemical pollution for aging populations and will help formulate initiatives for environmental protection. The book provides a comprehensive view of how environmental exposures may alter the health of our aging population. For readers engaged in environmental research, or aging research, it will highlight a number of questions that need more attention For other readers, they will learn something about the kind of exposures they should avoid or that they should prompt policy makers to reduce or eliminate.
D. J. McLachlan, B. A. Racette, J. E. Puzas, M. Lippmann, B. Fowler, R. R. Dietert, ... C. C. Bridges, Aging and Vulnerability to Environmental Chemicals: Age-related Disorders and their Origins in Environmental Exposures, The Royal Society of Chemistry, 2012.
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CHAPTER 1: Exposure to Lead and Cognitive Dysfunctionp5-30ByJennifer Weuve;Jennifer WeuveRush Institute for Healthy AgingRush University Medical Center, Chicago, ILUSADepartment of Environmental HealthHarvard School of Public Health, Boston, MAUSASearch for other works by this author on:Marc G. WeisskopfMarc G. WeisskopfDepartment of Environmental HealthHarvard School of Public Health, Boston, MAUSASearch for other works by this author on:
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CHAPTER 2: Cognitive Deterioration and Related Neuropathology in Older People with Alzheimer's Disease could Result from Life-Long Exposure to Aluminium Compoundsp31-82ByJ. R. WaltonJ. R. WaltonSearch for other works by this author on:
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CHAPTER 3: Do Polychlorinated Biphenyls and Associated Chemicals Exacerbate Aging-Related Declines in Brain Function?p83-103ByR. F. SeegalR. F. SeegalWadsworth Center, New York State Department of HealthEmpire State Plaza, P.O. Box 509, Albany, NY, 12201USADepartments of Environmental Health Sciences and Biomedical Sciences, School of Public HealthUniversity at AlbanyAlbany, NY, 12222USA[email protected]Search for other works by this author on:
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CHAPTER 4: Parkinson Diseasep104-124ByG. Nelson;G. NelsonUniversity of the WitwatersrandDivision of Biostatistics and Epidemiology, School of Public Health, Faculty of Health Sciences, 7 York Rd, Parktown, 2193South AfricaSearch for other works by this author on:B. A. RacetteB. A. RacetteUniversity of the WitwatersrandDivision of Biostatistics and Epidemiology, School of Public Health, Faculty of Health Sciences, 7 York Rd, Parktown, 2193South AfricaSearch for other works by this author on:
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CHAPTER 5: Mercuryp125-150ByHiroshi SatohHiroshi SatohProfessor Emeritus, Tohoku University, Food Safety CommissionAkasaka Park Bld. 22F 5-2-20 Akasaka, Minato-kuTokyo 107-6122[email protected]Search for other works by this author on:
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CHAPTER 6: Manganesep151-181ByRoberto G Lucchini;Roberto G LucchiniDepartment of Preventive Medicine, Mount Sinai School of MedicineNew York, NY 10029 and Occupational Medicine, University of BresciaItalySearch for other works by this author on:Donald R. Smith;Donald R. SmithDepartment of Microbiology and Environmental ToxicologyUniversity of CaliforniaSanta Cruz, CA 95064USASearch for other works by this author on:Ronald B TjalkensRonald B TjalkensDepartment of Environmental and Radiological Health SciencesColorado State UniversityFort Collins, CO 80523USA[email protected]Search for other works by this author on:
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CHAPTER 7: The Role of Persistent Organic Pollutants and Plastic-Associated Chemicals in Cardiovascular Disease and Metabolic Syndromep182-200ByLars Lind;Lars LindDept of Medical SciencesUppsala University, University Hospital Uppsala 751 85SwedenSearch for other works by this author on:P. Monica LindP. Monica LindOccupational and Environmental MedicineUppsala University, Ulleråkersvägen 40 Uppsala 751 85Sweden[email protected]Search for other works by this author on:
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CHAPTER 8: Obesity and Diabetes: Role of Environmental Chemical Exposuresp201-240ByThaddeus T. Schug;Thaddeus T. SchugNational Institute of Environmental Health Sciences, Division of Extramural Research and TrainingResearch Triangle ParkUSASearch for other works by this author on:Sarah G. Howard;Sarah G. HowardCollaborative on Health and the EnvironmentPO Box 316, Bolinas, CA 94924USASearch for other works by this author on:Kyla W. Taylor;Kyla W. TaylorNational Institute of Environmental Health Sciences, Office of Health Assessment and Translation, Division of National Toxicology ProgramResearch Triangle ParkNC, USA[email protected]Search for other works by this author on:Jerrold J. HeindelJerrold J. HeindelNational Institute of Environmental Health Sciences, Division of Extramural Research and TrainingResearch Triangle ParkUSASearch for other works by this author on:
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CHAPTER 9: Bisphenol A and Agingp241-266ByLaura N. VandenbergLaura N. VandenbergTufts UniversityCenter for Regenerative & Developmental Biology200 Boston Ave, Suite 4600, Medford, MA 02155USA[email protected]Search for other works by this author on:
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CHAPTER 10: Male Reproductive Tract Disordersp267-292ByJohn D. Meeker;John D. MeekerDepartment of Environmental Health SciencesUniversity of Michigan School of Public Health, Ann Arbor, MIUSA[email protected]Search for other works by this author on:Kelly K. FergusonKelly K. FergusonDepartment of Environmental Health SciencesUniversity of Michigan School of Public Health, Ann Arbor, MIUSA[email protected]Search for other works by this author on:
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CHAPTER 11: Breast Cancer – Importance of Life Stage with Respect to Environmental Influencesp293-330BySALLY S. WHITE;SALLY S. WHITEResearch Fellow, NTP Labs Branch, Division of the National Toxicology ProgramNIEHS/NIH, 111 TW Alexander Dr, Bldg 101, MD E1-08, Research Triangle Park, NC 27709USASearch for other works by this author on:SUZANNE E. FENTONSUZANNE E. FENTONGroup Leader, Reproductive Endocrinology, NTP Labs Branch, Division of the National Toxicology ProgramNIEHS/NIH, 111 TW Alexander Dr, Bldg 101, MD E1-08, Research Triangle Park, NC 27709USA[email protected]Search for other works by this author on:
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CHAPTER 12: Environmental Chemicals and Prostate Cancer Riskp331-345ByGail S. Prins'Gail S. Prins'Search for other works by this author on:
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CHAPTER 13: The Aging Kidney and Exposure to the Nephrotoxic Metals Cadmium and Mercuryp346-375ByChristy C. Bridges;Christy C. BridgesMercer University School of MedicineDivision of Basic Medical Sciences, Macon, Georgia 31207USA[email protected]Search for other works by this author on:Rudolfs K. ZalupsRudolfs K. ZalupsMercer University School of MedicineDivision of Basic Medical Sciences, Macon, Georgia 31207USA[email protected]Search for other works by this author on:
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CHAPTER 14: Age Related Effects of Cadmium and Possible Roles in Aging Processesp376-387ByBruce A FowlerBruce A FowlerSearch for other works by this author on:
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CHAPTER 15: Lead Exposure and Osteoporosis: Mechanisms and Clinical Manifestationsp388-408ByJ. Edward Puzas;J. Edward PuzasDepartment of OrthopaedicsUniversity of Rochester School of Medicine and DentistryRochester, NY 14642USA[email protected]Search for other works by this author on:Catherine A. Muzytchuk;Catherine A. MuzytchukDepartment of OrthopaedicsUniversity of Rochester School of Medicine and DentistryRochester, NY 14642USA[email protected]Search for other works by this author on:Jonathan D. HolzJonathan D. HolzDepartment of OrthopaedicsUniversity of Rochester School of Medicine and DentistryRochester, NY 14642USA[email protected]Search for other works by this author on:
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CHAPTER 16: Liver Diseasep409-435ByMatt Cave;Matt CaveDepartment of MedicineDivision of Gastroenterology, Hepatology, and Nutrition, Department of Pharmacology and Toxicology, University of Louisville, CTR Building Room 503, 505 S. Hancock St., Louisville, KY 40202USA[email protected]Search for other works by this author on:Mohammad K. Mohammad;Mohammad K. MohammadDepartment of MedicineDivision of Gastroenterology, Hepatology, and Nutrition, Department of Pharmacology and Toxicology, University of Louisville, CTR Building Room 503, 505 S. Hancock St., Louisville, KY 40202USA[email protected]Search for other works by this author on:Gavin Arteel;Gavin ArteelDepartment of MedicineDivision of Gastroenterology, Hepatology, and Nutrition, Department of Pharmacology and Toxicology, University of Louisville, CTR Building Room 503, 505 S. Hancock St., Louisville, KY 40202USA[email protected]Search for other works by this author on:Keith Cameron Falkner;Keith Cameron FalknerDepartment of MedicineDivision of Gastroenterology, Hepatology, and Nutrition, Department of Pharmacology and Toxicology, University of Louisville, CTR Building Room 503, 505 S. Hancock St., Louisville, KY 40202USA[email protected]Search for other works by this author on:Craig J. McClainCraig J. McClainDepartment of MedicineDivision of Gastroenterology, Hepatology, and Nutrition, Department of Pharmacology and Toxicology, University of Louisville, CTR Building Room 503, 505 S. Hancock St., Louisville, KY 40202USA[email protected]Search for other works by this author on:
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CHAPTER 17: Immune System Disordersp436-454ByRodney R. DietertRodney R. DietertDepartment of Microbiology and ImmunologyCollege of Veterinary Medicine, Cornell University, North Tower Rd. Ithaca, NY 14853USA[email protected]Search for other works by this author on:
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CHAPTER 18: Aging and Vulnerability to Ambient Air Pollutionp455-472ByMorton LippmannMorton LippmannNew York University School of MedicineNelson Institute of Environmental Medicine, 57 Old Forge Road, Tuxedo, NYUSA 10987[email protected]Search for other works by this author on:
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