Reducing, Refining and Replacing the Use of Animals in Toxicity Testing
Issues in Toxicology
Series Editors:
Professor Diana Anderson, University of Bradford, UK
Dr Michael D Waters, Integrated Laboratory Systems, Inc, N Carolina, USA
Dr Martin F Wilks, University of Basel, Switzerland
Dr Timothy C Marrs, Edentox Associates, Kent, UK
Titles in the Series:
1: Hair in Toxicology: An Important Bio-Monitor
2: Male-mediated Developmental Toxicity
3: Cytochrome P450: Role in the Metabolism and Toxicity of Drugs and other Xenobiotics
4: Bile Acids: Toxicology and Bioactivity
5: The Comet Assay in Toxicology
6: Silver in Healthcare
7: In Silico Toxicology: Principles and Applications
8: Environmental Cardiology
9: Biomarkers and Human Biomonitoring, Volume 1: Ongoing Programs and Exposures
10: Biomarkers and Human Biomonitoring, Volume 2: Selected Biomarkers of Current Interest
11: Hormone-Disruptive Chemical Contaminants in Food
12: Mammalian Toxicology of Insecticides
13: The Cellular Response to the Genotoxic Insult: The Question of Threshold for Genotoxic Carcinogens
14: Toxicological Effects of Veterinary Medicinal Products in Humans: Volume 1
15: Toxicological Effects of Veterinary Medicinal Products in Humans: Volume 2
16: Aging and Vulnerability to Environmental Chemicals: Age-related Disorders and their Origins in Environmental Exposures
17: Chemical Toxicity Prediction: Category Formation and Read-Across
18: The Carcinogenicity of Metals: Human Risk through Occupational and Environmental Exposure
19: Reducing, Refining and Replacing the Use of Animals in Toxicity Testing
How to obtain future titles on publication:
A standing order plan is available for this series. A standing order will bring delivery of each new volume immediately on publication.
For further information please contact:
Book Sales Department, Royal Society of Chemistry, Thomas Graham House,
Science Park, Milton Road, Cambridge, CB4 0WF, UK
Telephone: +44 (0)1223 420066, Fax: +44 (0)1223 420247
Email: [email protected]
Visit our website at www.rsc.org/books
Reducing, Refining and Replacing the Use of Animals in Toxicity Testing
Edited by
David G. Allen and Michael D. Waters
Integrated Laboratory Services, North Carolina, USA
Email: [email protected]
Issues in Toxicology No. 19
ISBN: 978-1-84973-652-7
ISSN: 1757-7179
A catalogue record for this book is available from the British Library
© The Royal Society of Chemistry 2014
All rights reserved
Apart from fair dealing for the purposes of research for non-commercial purposes or for private study, criticism or review, as permitted under the Copyright, Designs and Patents Act 1988 and the Copyright and Related Rights Regulations 2003, this publication may not be reproduced, stored or transmitted, in any form or by any means, without the prior permission in writing of The Royal Society of Chemistry or the copyright owner, or in the case of reproduction in accordance with the terms of licences issued by the Copyright Licensing Agency in the UK, or in accordance with the terms of the licences issued by the appropriate Reproduction Rights Organization outside the UK. Enquiries concerning reproduction outside the terms stated here should be sent to The Royal Society of Chemistry at the address printed on this page.
The RSC is not responsible for individual opinions expressed in this work.
Published by The Royal Society of Chemistry,
Thomas Graham House, Science Park, Milton Road,
Cambridge CB4 0WF, UK
Registered Charity Number 207890
For further information see our web site at www.rsc.org
