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This review presents a perspective of the important structural and synthetic studies reported in 2010. The strict definition of an organometallic compound as one containing at least one C-metal bond or contact has been used throughout the literature survey. As with previous years this review is not intended to be comprehensive, although it is based on a comprehensive search. Individual topics are highlighted in bold in the text in order to facilitate rapid access to a particular area of the literature. Research in 2010 on Group 2 and 12 organometallics was dominated by structural studies of novel types of compounds. This is reflected on the focus of the review for this year in particular.

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