Manganese in Health and Disease
Manganese in the diet is nutritionally essential for normal physiologic functioning. However, excessive exposure to manganese has been associated with developmental, neurodegenerative and other disorders.
The book comprehensively covers the toxicology of manganese. Leading investigators provide perspectives from toxicology, neuroscience, nutrition, molecular biology and risk assessment disciplines and chapters cover the toxicokinetics, toxicodynamic interactions and health effects of manganese, as well as its potential role in neurodegenerative diseases. A large section devoted to health effects presents the latest research that associates manganese exposure to potential human diseases.
Any scientists, health professional or regulator involved with metal exposure and toxicology should find this volume essential reading. Students and researchers in neurotoxicology will also find this book a useful reference.
Manganese in Health and Disease, The Royal Society of Chemistry, 2014.
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Table of contents
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CHAPTER 1: Manganese Transport, Trafficking and Function in Invertebratesp1-33ByAmornrat Naranuntarat Jensen;Amornrat Naranuntarat JensenDepartment of Pathobiology, Faculty of Science, Mahidol UniversityBangkokThailandSearch for other works by this author on:Laran T. JensenLaran T. JensenSearch for other works by this author on:
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Chapter 2: Nutritional Requirements for Manganesep34-75ByNamrata SanjeeviNamrata SanjeeviSearch for other works by this author on:
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Chapter 3: Manganese Superoxide Dismutasep77-118ByKinsley K. KininghamKinsley K. KininghamBelmont University College of Pharmacy, Department of Pharmaceutical, Social and Administrative SciencesNashvilleTNUSA[email protected]Search for other works by this author on:
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Chapter 4: Olfactory Transport of Manganese: Implications for Neurotoxicityp119-132ByMelanie L. FosterMelanie L. FosterSearch for other works by this author on:
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Chapter 5: Manganese Transport Across the Pulmonary Epitheliump133-157ByKhristy J. Thompson;Khristy J. ThompsonHarvard School of Public HealthBostonMAUSASearch for other works by this author on:Marianne Wessling-ResnickMarianne Wessling-ResnickHarvard School of Public HealthBostonMAUSASearch for other works by this author on:
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Chapter 6: Are There Distinguishable Roles for the Different Oxidation States of Manganese in Manganese Toxicity?p158-181ByThomas E. GunterThomas E. GunterDepartment of Biochemistry and Biophysics, University of Rochester Medical CenterRochesterNYUSA[email protected]Search for other works by this author on:
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Chapter 7: Effect of Manganese on Signaling Pathwaysp182-198ByTanara V. Peres;Tanara V. PeresUniversidade Federal de Santa Catarina, Centro de Ciências Biológicas, Departamento de BioquímicaFlorianópolisBrazil[email protected]Search for other works by this author on:Fabiano M. Cordova;Fabiano M. CordovaUniversidade Federal de Santa Catarina, Centro de Ciências Biológicas, Departamento de BioquímicaFlorianópolisBrazil[email protected]Search for other works by this author on:Mark W. Lopes;Mark W. LopesUniversidade Federal de Santa Catarina, Centro de Ciências Biológicas, Departamento de BioquímicaFlorianópolisBrazil[email protected]Search for other works by this author on:Ana Paula Costa;Ana Paula CostaUniversidade Federal de Santa Catarina, Centro de Ciências Biológicas, Departamento de BioquímicaFlorianópolisBrazil[email protected]Search for other works by this author on:Rodrigo Bainy LealRodrigo Bainy LealUniversidade Federal de Santa Catarina, Centro de Ciências Biológicas, Departamento de BioquímicaFlorianópolisBrazil[email protected]Search for other works by this author on:
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Chapter 8: Manganese and Oxidative Stressp199-220ByDaiana Silva Ávila;Daiana Silva ÁvilaUniversidade Federal do Pampa-UNIPAMPA UruguaianaUruguaianaRSBrazilSearch for other works by this author on:Marcelo Farina;Marcelo FarinaDepartamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa CatarinaFlorianópolisSCBrazilSearch for other works by this author on:João Batista Teixeira da Rocha;João Batista Teixeira da RochaDepartamento de Química, Universidade Federal de Santa MariaSanta MariaRSBrazilSearch for other works by this author on:Michael AschnerMichael AschnerDepartment of Molecular Pharmacology, Albert Einstein College of MedicineBronxNYUSA[email protected]Search for other works by this author on:
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Chapter 9: Mutual Neurotoxic Mechanisms Controlling Manganism and Parkisonismp221-257ByJerome A. RothJerome A. RothSearch for other works by this author on:
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Chapter 10: Mechanism of Manganese-Induced Impairment of Astrocytic Glutamate Transportersp258-278ByPratap Karki;Pratap KarkiDepartment of Physiology, Meharry Medical CollegeNashvilleTNUSASearch for other works by this author on:Keisha Smith;Keisha SmithDepartment of Physiology, Meharry Medical CollegeNashvilleTNUSASearch for other works by this author on:Michael Aschner;Michael AschnerDepartment of Molecular Pharmacology, Albert Einstein College of MedicineBronxNYUSA[email protected]Search for other works by this author on:Eunsook LeeEunsook LeeDepartment of Physiology, Meharry Medical CollegeNashvilleTNUSASearch for other works by this author on:
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Chapter 11: Impairment of Glutamine/Glutamate-γ-aminobutyric Acid Cycle in Manganese Toxicity in the Central Nervous Systemp279-296ByMarta Sidoryk-Wegrzynowicz;Marta Sidoryk-WegrzynowiczCambridge Centre of Brain Repair, University of CambridgeCambridgeUKSearch for other works by this author on:Michael AschnerMichael AschnerSearch for other works by this author on:
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Chapter 12: Manganese and Neuroinflammationp297-321ByKelly A. Kirkley;Kelly A. KirkleyCenter for Environmental Medicine, Colorado State UniversityFort CollinsCOUSADepartment of Environmental and Radiological Health Sciences, Colorado State UniversityFort CollinsCOUSA[email protected]Search for other works by this author on:Ronald B. TjalkensRonald B. TjalkensCenter for Environmental Medicine, Colorado State UniversityFort CollinsCOUSADepartment of Environmental and Radiological Health Sciences, Colorado State UniversityFort CollinsCOUSA[email protected]Search for other works by this author on:
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Chapter 13: Modeling Manganese Kinetics for Human Health Risk Assessmentp322-354ByMiyoung Yoon;Miyoung YoonThe Hamner Institutes for Health Sciences, Research Triangle ParkNCUSASearch for other works by this author on:Harvey J. Clewell;Harvey J. ClewellThe Hamner Institutes for Health Sciences, Research Triangle ParkNCUSASearch for other works by this author on:Melvin E. AndersenMelvin E. AndersenThe Hamner Institutes for Health Sciences, Research Triangle ParkNCUSASearch for other works by this author on:
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Chapter 14: Significance and Usefulness of Biomarkers of Exposure to Manganesep355-401ByPerrine Hoet;Perrine HoetUniversité catholique de Louvain (UCL), Institut de Recherche Expérimentale et Clinique (IREC), Louvain Centre for Toxicology and Applied Pharmacology (LTAP)BruxellesBelgium[email protected][email protected]Search for other works by this author on:Harry A. RoelsHarry A. RoelsUniversité catholique de Louvain (UCL), Institut de Recherche Expérimentale et Clinique (IREC), Louvain Centre for Toxicology and Applied Pharmacology (LTAP)BruxellesBelgium[email protected][email protected]Search for other works by this author on:
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Chapter 15: Manganese and Parenteral Nutritionp403-425ByJudy L. Aschner;Judy L. AschnerDepartment of Pediatrics, The Children's Hospital at Montefiore and The Albert Einstein College of Medicine of Yeshiva University1300 Morris Park Avenue – Belfer 706BronxNY 10461USASearch for other works by this author on:Nathalie L. MaitreNathalie L. MaitreDepartment of Pediatrics, Vanderbilt Kennedy Center for Human Development, Vanderbilt Center for Molecular Toxicology, Vanderbilt University Medical Center11111 Doctor's Office Tower, 2200 Children's WayNashvilleTN 37232-9544USA[email protected]Search for other works by this author on:
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Chapter 16: Developmental Effects of Manganesep426-436ByScott M. Langevin;Scott M. LangevinDepartment of Environmental Health, University of Cincinnati College of MedicineCincinnatiOHUSA[email protected]Search for other works by this author on:Erin N. HaynesErin N. HaynesDepartment of Environmental Health, University of Cincinnati College of MedicineCincinnatiOHUSA[email protected]Search for other works by this author on:
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Chapter 17: The Effects of Manganese on Female Pubertal Developmentp437-458ByWilliam L. Dees;William L. DeesDepartment of Veterinary Integrative Biosciences, College of Veterinary Medicine, Texas A&M UniversityCollege StationTexasUSA[email protected]Search for other works by this author on:Jill K. Hiney;Jill K. HineyDepartment of Veterinary Integrative Biosciences, College of Veterinary Medicine, Texas A&M UniversityCollege StationTexasUSA[email protected]Search for other works by this author on:Vinod K. SrivastavaVinod K. SrivastavaDepartment of Veterinary Integrative Biosciences, College of Veterinary Medicine, Texas A&M UniversityCollege StationTexasUSA[email protected]Search for other works by this author on:
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Chapter 18: A Decade of Studies on Manganese Neurotoxicity in Non-Human Primates: Novel Findings and Future Directionsp459-476ByTomás R. GuilarteTomás R. GuilarteDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University722 West 168th St., Room 1105-ENew YorkNY 10032USA[email protected]Search for other works by this author on:
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Chapter 19: Imaging Modalities for Manganese Toxicityp477-512ByUlrike Dydak;Ulrike DydakSchool of Health Sciences, Purdue University550 Stadium Mall DriveWest LafayetteIndiana 47907USADepartment of Radiology and Imaging Sciences, Indiana University School of MedicineIndianapolisIndiana USASearch for other works by this author on:Susan R. CriswellSusan R. CriswellDepartment of Neurology, Washington University School of MedicineSt. LouisMissouriUSAAmerican Parkinson Disease Association Advanced Center for Parkinson ResearchSt. LouisMissouriUSA[email protected]Search for other works by this author on:
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Chapter 20: Epidemiological Studies of Parkinsonism in Weldersp513-523ByHarvey Checkoway;Harvey CheckowayDepartment of Family and Preventive Medicine, University of CaliforniaSan DiegoLa Jolla, CaliforniaUSASearch for other works by this author on:Susan Searles Nielsen;Susan Searles NielsenDepartment of Environmental and Occupational Health Sciences, University of WashingtonSeattleWashingtonUSASearch for other works by this author on:Brad A. RacetteBrad A. RacetteSearch for other works by this author on:
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Chapter 21: Cognitive Effects of Manganese in Children and Adultsp524-539ByRoberto Lucchini;Roberto LucchiniDepartment of Preventive Medicine, Icahn School of Medicine at Mount SinaiNew YorkSearch for other works by this author on:Silvia ZoniSilvia ZoniSearch for other works by this author on:
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Chapter 22: Manganese and Huntington Diseasep540-573ByAndrew M. Tidball;Andrew M. TidballVanderbilt University Medical Center465 21st Avenue South, 6140 MRB3NashvilleTN 37232-8552USA[email protected]Search for other works by this author on:Terry Jo Bichell;Terry Jo BichellVanderbilt University Medical Center465 21st Avenue South, 6140 MRB3NashvilleTN 37232-8552USA[email protected]Search for other works by this author on:Aaron B. BowmanAaron B. BowmanVanderbilt University Medical Center465 21st Avenue South, 6140 MRB3NashvilleTN 37232-8552USA[email protected]Search for other works by this author on:
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Chapter 23: Manganese and Prion Diseasep574-603ByHuajun Jin;Huajun JinParkinson's Disorder Research Laboratory, Iowa Center for Advanced Neurotoxicology, Department of Biomedical Sciences, Iowa State UniversityAmesIowa 50011USA[email protected]Search for other works by this author on:Dilshan S. Harischandra;Dilshan S. HarischandraParkinson's Disorder Research Laboratory, Iowa Center for Advanced Neurotoxicology, Department of Biomedical Sciences, Iowa State UniversityAmesIowa 50011USA[email protected]Search for other works by this author on:Christopher Choi;Christopher ChoiParkinson's Disorder Research Laboratory, Iowa Center for Advanced Neurotoxicology, Department of Biomedical Sciences, Iowa State UniversityAmesIowa 50011USA[email protected]Search for other works by this author on:Dustin Martin;Dustin MartinParkinson's Disorder Research Laboratory, Iowa Center for Advanced Neurotoxicology, Department of Biomedical Sciences, Iowa State UniversityAmesIowa 50011USA[email protected]Search for other works by this author on:Vellareddy Anantharam;Vellareddy AnantharamParkinson's Disorder Research Laboratory, Iowa Center for Advanced Neurotoxicology, Department of Biomedical Sciences, Iowa State UniversityAmesIowa 50011USA[email protected]Search for other works by this author on:Arthi Kanthasamy;Arthi KanthasamyParkinson's Disorder Research Laboratory, Iowa Center for Advanced Neurotoxicology, Department of Biomedical Sciences, Iowa State UniversityAmesIowa 50011USA[email protected]Search for other works by this author on:Anumantha G. KanthasamyAnumantha G. KanthasamyParkinson's Disorder Research Laboratory, Iowa Center for Advanced Neurotoxicology, Department of Biomedical Sciences, Iowa State UniversityAmesIowa 50011USA[email protected]Search for other works by this author on:
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Chapter 24: DNA Damage Induced by Manganesep604-620ByJulia Bornhorst;Julia BornhorstInstitute of Nutritional Sciences, University of PotsdamArthur-Scheunert-Allee 114-11614558NuthetalGermany[email protected][email protected]Search for other works by this author on:Tanja SchwerdtleTanja SchwerdtleInstitute of Nutritional Sciences, University of PotsdamArthur-Scheunert-Allee 114-11614558NuthetalGermany[email protected][email protected]Search for other works by this author on:
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