The Handbook of Continuous Crystallization
Continuous crystallization is an area of intense research, with particular respect to the pharmaceutical industry and fine chemicals. Improvements in continuous crystallization technologies offer chemical industries significant financial gains, through reduced expenditure and operational costs, and consistent product quality.
Written by well-known leaders in the field, The Handbook of Continuous Crystallization presents fundamental and applied knowledge, with attention paid to application and scaling up, and the burgeoning area of process intensification. Beginning with concepts around crystallization techniques and control strategies, the reader will learn about experimental methods and computational tools. Case studies spanning fine and bulk chemicals, the pharmaceutical industry, and employing new mathematical tools, put theory into context.
The Handbook of Continuous Crystallization, The Royal Society of Chemistry, 2020.
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CHAPTER 1: Nucleation and Crystal Growth in Continuous Crystallization1p1-50ByJohn McGinty;John McGintyEPSRC Centre for Innovative Manufacturing in Continuous Manufacturing and Crystallisation, University of StrathclydeGlasgowUKSearch for other works by this author on:Chris Price;Chris PriceEPSRC Centre for Innovative Manufacturing in Continuous Manufacturing and Crystallisation, University of StrathclydeGlasgowUKSearch for other works by this author on:Joop H. ter Horst;Joop H. ter HorstEPSRC Centre for Innovative Manufacturing in Continuous Manufacturing and Crystallisation, University of StrathclydeGlasgowUKSearch for other works by this author on:Jan SefcikJan SefcikEPSRC Centre for Innovative Manufacturing in Continuous Manufacturing and Crystallisation, University of StrathclydeGlasgowUKSearch for other works by this author on:
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CHAPTER 2: Fundamentals of Population Balance Based Crystallization Process Modelingp51-101ByBotond Szilagyi;Botond SzilagyiDavidson School of Chemical Engineering, Purdue UniversityWest LafayetteIN 47907-2100USA[email protected]Search for other works by this author on:Aniruddha Majumder;Aniruddha MajumderSchool of Engineering, University of AberdeenAberdeen AB24 3UEUKSearch for other works by this author on:Zoltan K. NagyZoltan K. NagyDavidson School of Chemical Engineering, Purdue UniversityWest LafayetteIN 47907-2100USA[email protected]Department of Chemical Engineering, Loughborough UniversityLoughboroughLE11 3TUUKSearch for other works by this author on:
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CHAPTER 3: Continuous Crystallisation With Oscillatory Baffled Crystalliser Technologyp102-171ByXiongwei NiXiongwei NiSchool of Engineering and Physical Sciences, Heriot-Watt UniversityEdinburgh EH14 4ASUK[email protected]Search for other works by this author on:
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CHAPTER 4: Process Controlp172-218ByR. Lakerveld;R. LakerveldThe Hong Kong University of Science and Technology, Department of Chemical and Biological EngineeringClear Water BayHong KongChina[email protected]Search for other works by this author on:B. BenyahiaB. BenyahiaLoughborough University, Department of Chemical EngineeringLeicestershireUKSearch for other works by this author on:
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CHAPTER 5: Slug-flow Continuous Crystallization: Fundamentals and Process Intensificationp219-247ByJ. Carl Pirkle, Jr;J. Carl Pirkle, JrMassachusetts Institute of Technology, Department of Chemical Engineering77 Massachusetts AvenueCambridgeMassachusetts 02139USA[email protected][email protected][email protected][email protected]Search for other works by this author on:Michael L. Rasche;Michael L. RascheMassachusetts Institute of Technology, Department of Chemical Engineering77 Massachusetts AvenueCambridgeMassachusetts 02139USA[email protected][email protected][email protected][email protected]Search for other works by this author on:Richard D. Braatz;Richard D. BraatzMassachusetts Institute of Technology, Department of Chemical Engineering77 Massachusetts AvenueCambridgeMassachusetts 02139USA[email protected][email protected][email protected][email protected]Search for other works by this author on:Mo JiangMo JiangMassachusetts Institute of Technology, Department of Chemical Engineering77 Massachusetts AvenueCambridgeMassachusetts 02139USA[email protected][email protected][email protected][email protected]Virginia Commonwealth University, Department of Chemical and Life Science Engineering601 West Main StreetBox 843068RichmondVirginia 23284-3068USASearch for other works by this author on:
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CHAPTER 6: Continuous Crystallization of Bulk and Fine Chemicalsp248-265ByMatthias KindMatthias KindKarlsruhe Institute of Technology, Department of Chemical and Process EngineeringKaiserstr. 12KarlsruheD-76131Germany[email protected]Search for other works by this author on:
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CHAPTER 7: Process Intensification in Continuous Crystallizationp266-320ByT. Stelzer;T. StelzerUniversity of Puerto Rico, Department of Pharmaceutical SciencesPO Box 365067San JuanPR 00936USA[email protected]Crystallization Design Institute, Molecular Sciences Research Center1390 Ponce De León AvenueSan JuanPR 00926USASearch for other works by this author on:R. Lakerveld;R. LakerveldThe Hong Kong University of Science and Technology, Department of Chemical and Biological EngineeringClear Water BayKowloonHong KongSearch for other works by this author on:A. S. MyersonA. S. MyersonMassachusetts Institute of Technology, Department of Chemical Engineering77 Massachusetts Ave.MA 02139CambridgeUSASearch for other works by this author on:
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CHAPTER 8: Continuous Membrane Crystallizationp321-352ByEfrem Curcio;Efrem CurcioDepartment of Environmental and Chemical Engineering DIATIC, University of CalabriaVia P. Bucci Cubo 45A87036 RendeCSItaly[email protected]Institute on Membrane Technology, National Research Council of Italy ITM-CNRVia P. Bucci Cubo 17C87036 RendeCSItaly[email protected]Search for other works by this author on:Gianluca Di ProfioGianluca Di ProfioInstitute on Membrane Technology, National Research Council of Italy ITM-CNRVia P. Bucci Cubo 17C87036 RendeCSItaly[email protected]Search for other works by this author on:
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CHAPTER 9: Process Analytical Technology in Continuous Crystallization1p353-371ByL. L. Simon;L. L. SimonNew Active Ingredients Process Technology, Syngenta Crop Protection AGBreitenloh 5CH-4333 MünchwilenSwitzerland[email protected]Search for other works by this author on:E. SimoneE. SimoneSearch for other works by this author on:
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CHAPTER 10: Continuous Protein Crystallizationp372-392ByWenqian Chen;Wenqian ChenImperial College London, Department of Chemical Engineering, South Kensington CampusLondon SW7 2AZUK[email protected]Search for other works by this author on:Huaiyu Yang;Huaiyu YangImperial College London, Department of Chemical Engineering, South Kensington CampusLondon SW7 2AZUK[email protected]Search for other works by this author on:Jerry Yong Yew HengJerry Yong Yew HengImperial College London, Department of Chemical Engineering, South Kensington CampusLondon SW7 2AZUK[email protected]Search for other works by this author on:
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CHAPTER 11: Continuous Melt Crystallizationp393-421ByHongxun Hao;Hongxun HaoTianjin University, National Engineering Research Center of Industrial Crystallization Technology, School of Chemical Engineering and TechnologyTianjin 300072PR China[email protected]Collaborative Innovation Center of Chemical Science and Chemical Engineering (Tianjin)Tianjin 300072PR ChinaSearch for other works by this author on:Yan XiaoYan XiaoTianjin University, National Engineering Research Center of Industrial Crystallization Technology, School of Chemical Engineering and TechnologyTianjin 300072PR China[email protected]Collaborative Innovation Center of Chemical Science and Chemical Engineering (Tianjin)Tianjin 300072PR ChinaSearch for other works by this author on:
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CHAPTER 12: Continuous Enantioselective Crystallization of Chiral Compoundsp422-468ByHeike Lorenz;Heike LorenzMax Planck Institute for Dynamics of Complex Technical SystemsSandtorstrasse 1D-39106 MagdeburgGermany[email protected]Search for other works by this author on:Erik Temmel;Erik TemmelMax Planck Institute for Dynamics of Complex Technical SystemsSandtorstrasse 1D-39106 MagdeburgGermany[email protected]Search for other works by this author on:Andreas Seidel-MorgensternAndreas Seidel-MorgensternMax Planck Institute for Dynamics of Complex Technical SystemsSandtorstrasse 1D-39106 MagdeburgGermany[email protected]Otto von Guericke University, Institute of Process EngineeringUniversitätsplatz 1D-39106 MagdeburgGermanySearch for other works by this author on:
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CHAPTER 13: Continuous Isolation of Active Pharmaceutical Ingredientsp469-507ByC. J. Price;C. J. PriceUniversity of Strathclyde, Department of Chemical and Process EngineeringMontrose StreetGlasgowG1 1XQScotlandUK[email protected]Search for other works by this author on:A. Barton;A. BartonAlconbury Weston LtdOldfield House, Galveston GroveStoke-on-trent, StaffordshireEnglandST4 3PEUKSearch for other works by this author on:S. J. ColemanS. J. ColemanAlconbury Weston LtdOldfield House, Galveston GroveStoke-on-trent, StaffordshireEnglandST4 3PEUKSearch for other works by this author on:
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CHAPTER 14: Continuous Eutectic Freeze Crystallizationp508-541ByJemitias Chivavava;Jemitias ChivavavaCrystallization and Precipitation Research Unit, Department of Chemical Engineering, University of Cape TownPrivate BagRondebosch7701Cape TownSouth Africa[email protected]Search for other works by this author on:Debbie Jooste;Debbie JoosteCrystallization and Precipitation Research Unit, Department of Chemical Engineering, University of Cape TownPrivate BagRondebosch7701Cape TownSouth Africa[email protected]Search for other works by this author on:Benita Aspeling;Benita AspelingCrystallization and Precipitation Research Unit, Department of Chemical Engineering, University of Cape TownPrivate BagRondebosch7701Cape TownSouth Africa[email protected]Search for other works by this author on:Edward Peters;Edward PetersCrystallization and Precipitation Research Unit, Department of Chemical Engineering, University of Cape TownPrivate BagRondebosch7701Cape TownSouth Africa[email protected]Search for other works by this author on:Dereck Ndoro;Dereck NdoroCrystallization and Precipitation Research Unit, Department of Chemical Engineering, University of Cape TownPrivate BagRondebosch7701Cape TownSouth Africa[email protected]Search for other works by this author on:Hilton Heydenrych;Hilton HeydenrychCrystallization and Precipitation Research Unit, Department of Chemical Engineering, University of Cape TownPrivate BagRondebosch7701Cape TownSouth Africa[email protected]Search for other works by this author on:Marcos Rodriguez Pascual;Marcos Rodriguez PascualCrystallization and Precipitation Research Unit, Department of Chemical Engineering, University of Cape TownPrivate BagRondebosch7701Cape TownSouth Africa[email protected]Search for other works by this author on:Alison LewisAlison LewisCrystallization and Precipitation Research Unit, Department of Chemical Engineering, University of Cape TownPrivate BagRondebosch7701Cape TownSouth Africa[email protected]Search for other works by this author on:
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CHAPTER 15: Economic Analysis of Continuous Crystallisation1p542-576BySamir Diab;Samir DiabInstitute for Materials and Processes (IMP), School of Engineering, University of EdinburghThe King's BuildingsEdinburghEH9 3FBUK[email protected]Search for other works by this author on:Hikaru G. Jolliffe;Hikaru G. JolliffeEPSRC Centre for Innovative Manufacturing in Continuous Manufacturing and Crystallisation, University of StrathclydeGlasgowG1 1RDUKSearch for other works by this author on:Dimitrios I. GerogiorgisDimitrios I. GerogiorgisInstitute for Materials and Processes (IMP), School of Engineering, University of EdinburghThe King's BuildingsEdinburghEH9 3FBUK[email protected]Search for other works by this author on:
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CHAPTER 16: Digital Design and Operation of Continuous Crystallization Processes via Mechanistic Modelling Toolsp577-601ByChristopher L. Burcham;Christopher L. BurchamEli Lilly & Co. Inc.IndianapolisIndianaUSASearch for other works by this author on:Christopher S. Polster;Christopher S. PolsterEli Lilly & Co. Inc.IndianapolisIndianaUSASearch for other works by this author on:Furqan Tahir;Furqan TahirPerceptive Engineering Ltd.DaresburyUKSearch for other works by this author on:John MackJohn MackPerceptive Engineering Ltd.DaresburyUKSearch for other works by this author on:
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