Vitamin E: Chemistry and Nutritional Benefits
Vitamin E was discovered in 1922 by Evans and Bishop as an essential micronutrient for reproduction in rats. The active substance was isolated in 1936 by Evans and was named tocopherol, although the tocopherols and tocotrienols are actually a group of eight isomeric molecules that are characterized by a chromanol ring structure and a side chain.
Providing an overview of the state-of-the-art of the chemistry of vitamin E, this book reflects the issues stemming from the complexity of the role and actions in vivo as well as in vitro. It summarizes information on the properties and function of vitamin E, the current understanding of the advantages and limitations of it, and also its application in promotion of health and prevention of diseases. Based on sound, solid scientific evidence, this is a timely addition to the literature as the centennial anniversary of the discovery of this important vitamin approaches.
Vitamin E: Chemistry and Nutritional Benefits, The Royal Society of Chemistry, 2019.
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CHAPTER 1: Vitamin E: Structure, Properties and Functionsp1-11ByEtsuo Niki;Etsuo NikiUniversity of Tokyo, Research Center for Advanced Science and Technology (RCAST)KomabaTokyo 153-8904Japan[email protected]Search for other works by this author on:Kouichi AbeKouichi AbeSSCI Laboratories, Faculty of Pharmacology, Musashino UniversityNishi-Tokyo-ShiTokyo 202-0023JapanSearch for other works by this author on:
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CHAPTER 2: Tocotrienols: From Bench to Bedsidep12-31ByJu-Yen Fu;Ju-Yen FuNutrition Unit, Product Development and Advisory Services, Malaysian Palm Oil Board6 Persiaran Institusi, Bandar Baru Bangi43000 KajangSelangorMalaysia[email protected][email protected]Search for other works by this author on:Geetha Maniam;Geetha ManiamNutrition Unit, Product Development and Advisory Services, Malaysian Palm Oil Board6 Persiaran Institusi, Bandar Baru Bangi43000 KajangSelangorMalaysia[email protected][email protected]Department of Pharmaceutical Chemistry, School of Pharmacy, International Medical University126, Jalan Jalil Perkasa 19Bukit Jalil57000 Kuala LumpurMalaysiaSearch for other works by this author on:Fu-Shun Wong;Fu-Shun WongNutrition Unit, Product Development and Advisory Services, Malaysian Palm Oil Board6 Persiaran Institusi, Bandar Baru Bangi43000 KajangSelangorMalaysia[email protected][email protected]Department of Pharmacology, Faculty of Medicine, University of Malaya50603 Kuala LumpurMalaysiaSearch for other works by this author on:Doryn Meam-Yee Tan;Doryn Meam-Yee TanNutrition Unit, Product Development and Advisory Services, Malaysian Palm Oil Board6 Persiaran Institusi, Bandar Baru Bangi43000 KajangSelangorMalaysia[email protected][email protected]School of Pharmacy, Monash University MalaysiaJalan Lagoon Selatan47500 Bandar SunwaySelangorMalaysiaSearch for other works by this author on:Puvaneswari Meganathan;Puvaneswari MeganathanNutrition Unit, Product Development and Advisory Services, Malaysian Palm Oil Board6 Persiaran Institusi, Bandar Baru Bangi43000 KajangSelangorMalaysia[email protected][email protected]Department of Pharmacology, Faculty of Medicine, University of Malaya50603 Kuala LumpurMalaysiaSearch for other works by this author on:Lay-Hong ChuahLay-Hong ChuahSchool of Pharmacy, Monash University MalaysiaJalan Lagoon Selatan47500 Bandar SunwaySelangorMalaysiaAdvanced Engineering Platform, Monash University MalaysiaJalan Lagoon Selatan47500 Bandar SunwaySelangorMalaysiaSearch for other works by this author on:
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CHAPTER 3: The Behaviour of Vitamin E in Membranesp32-50ByJ. Atkinson;J. AtkinsonBrock University, Department of Chemistry1812 Sir Isaac Brock WaySt. CatharinesOntarioL2S3A1Canada[email protected]Search for other works by this author on:D. Marquardt;D. MarquardtUniversity of Windsor, Department of Chemistry and Biochemistry401 Sunset Ave.WindsorOntarioN9B3P4CanadaSearch for other works by this author on:T. HarrounT. HarrounBrock University, Department of Physics1812 Sir Isaac Brock WaySt. CatharinesOntarioL2S3A1CanadaSearch for other works by this author on:
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CHAPTER 4: Chemical Reactivity and Cellular Uptake of Tocopherols and Tocotrienolsp51-63ByYoshiro Saito;Yoshiro SaitoSystems Life Sciences Laboratory, Department of Medical Life Systems, Faculty of Life and Medical Sciences, Doshisha UniversityKyotanabeKyoto 610-0394Japan[email protected]Search for other works by this author on:Yasukazu YoshidaYasukazu YoshidaHealth Research Institute, National Institute of Advanced Industrial Science and Technology (AIST)TakamatsuKagawa 761-0395Japan[email protected]Search for other works by this author on:
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CHAPTER 5: α-Tocopherol Transfer Proteinp64-74ByNozomu Kono;Nozomu KonoGraduate School of Pharmaceutical Sciences, the University of Tokyo7-3-1 HongoBunkyo-kuTokyo 113-0033Japan[email protected]Search for other works by this author on:Hiroyuki AraiHiroyuki AraiGraduate School of Pharmaceutical Sciences, the University of Tokyo7-3-1 HongoBunkyo-kuTokyo 113-0033Japan[email protected]Search for other works by this author on:
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CHAPTER 6: Tocopheryl Phosphatep75-87ByAngelo AzziAngelo AzziVascular Biology Laboratory, JM USDA-HNRCA at Tufts University711 Washington St.BostonMA 02111USA[email protected]Search for other works by this author on:
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CHAPTER 7: Novel Functions of Vitamin E Nicotinatep88-97ByY. J. Suzuki;Y. J. SuzukiDepartment of Pharmacology and Physiology, Georgetown University Medical CenterWashington, DC 20057USA[email protected]Search for other works by this author on:L. Marcocci;L. MarcocciDepartment of Biochemical Sciences “A. Rossi Fanelli”, Sapienza University of RomeRomeItalySearch for other works by this author on:K. R. Duncan;K. R. DuncanDepartment of Pharmacology and Physiology, Georgetown University Medical CenterWashington, DC 20057USA[email protected]Search for other works by this author on:D. I. Suzuki;D. I. SuzukiDepartment of Pharmacology and Physiology, Georgetown University Medical CenterWashington, DC 20057USA[email protected]Search for other works by this author on:N. V. ShultsN. V. ShultsDepartment of Pharmacology and Physiology, Georgetown University Medical CenterWashington, DC 20057USA[email protected]Search for other works by this author on:
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CHAPTER 8: Reactive Oxygen Species in Biological Systemsp98-117ByChristine C. WinterbournChristine C. WinterbournDepartment of Pathology and Biomedical Science, University of Otago ChristchurchChristchurch, 2 Riccarton AveChristchurch 8011New Zealand[email protected]Search for other works by this author on:
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CHAPTER 9: Lipid Peroxidation: Role of Vitamin Ep118-133ByShanshan Zhong;Shanshan ZhongCAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences (SIBS), Chinese Academy of Sciences (CAS)Shanghai 200031China[email protected]University of Chinese Academy of Sciences, CASBeijing 100049ChinaSearch for other works by this author on:Huiyong YinHuiyong YinCAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences (SIBS), Chinese Academy of Sciences (CAS)Shanghai 200031China[email protected]University of Chinese Academy of Sciences, CASBeijing 100049ChinaSchool of Life Science and Technology, ShanghaiTech UniversityShanghai 200031ChinaSearch for other works by this author on:
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CHAPTER 10: Antioxidant Defense Network and Vitamin Ep134-150ByEtsuo NikiEtsuo NikiResearch Center for Advanced Science and Technology, University of Tokyo153-8904Japan[email protected]Search for other works by this author on:
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CHAPTER 11: Vitamin E Inspired Synthetic Antioxidantsp151-164ByLuca Valgimigli;Luca ValgimigliDepartment of Chemistry “G. Ciamician”, University of BolognaVia S. Giacomo 1140126 BolognaItaly[email protected]Search for other works by this author on:Riccardo AmoratiRiccardo AmoratiDepartment of Chemistry “G. Ciamician”, University of BolognaVia S. Giacomo 1140126 BolognaItaly[email protected]Search for other works by this author on:
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CHAPTER 12: Action of Vitamin E Against Lipid Peroxidation and Cell Deathp165-174ByNoriko NoguchiNoriko NoguchiSystems Life Sciences Laboratory, Department of Medical Life Systems, Faculty of Life and Medical Sciences, Doshisha University1-3 Miyakodani, TataraKyotanabeKyoto 610-0394Japan[email protected]Search for other works by this author on:
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CHAPTER 13: Oxidation Products of Vitamin E with Lipid-derived Free Radicalsp175-188ByRyo YamauchiRyo YamauchiGifu University, Department of Applied Life Science, Faculty of Applied Biological Sciences1-1 YanagidoGifu CityGifu 501-1193Japan[email protected]Search for other works by this author on:
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CHAPTER 14: Metabolism of Vitamin Ep189-207ByRegina Brigelius-FlohéRegina Brigelius-FlohéGerman Institute of Human Nutrition Potsdam-RehbrueckeArthur-Scheunert-Allee 114-11614558 NuthetalGermany[email protected]Search for other works by this author on:
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CHAPTER 15: Analysis of Vitamin E Metabolitesp208-227ByDanilo Giusepponi;Danilo GiusepponiIstituto Zooprofilattico Sperimentale Umbria e Marche “Togo Rosati”PerugiaItalySearch for other works by this author on:Roberta Galarini;Roberta GalariniIstituto Zooprofilattico Sperimentale Umbria e Marche “Togo Rosati”PerugiaItalySearch for other works by this author on:Francesco GalliFrancesco GalliSearch for other works by this author on:
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CHAPTER 16: Essentiality, Bioavailability, and Health Benefits of α-Tocopherol Stereoisomersp228-241ByRichard S. BrunoRichard S. BrunoThe Ohio State University, Human Nutrition Program1787 Neil Ave, 325 Campbell HallColumbusOH 43210USA[email protected]Search for other works by this author on:
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CHAPTER 17: Vitamin E Deficiency and Inadequacy; Insights Using Zebrafish, Lipidomics and Metabolomicsp242-256ByMaret G. TraberMaret G. TraberSearch for other works by this author on:
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CHAPTER 18: Interference Effect of Vitamin E on Vitamin K Metabolismp257-265BySaiko IkedaSaiko IkedaDepartment of Nutritional Sciences, Nagoya University of Arts and Sciences57 Takenoyama, IwasakiNisshinAichi 470-0196Japan[email protected]Search for other works by this author on:
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