Chemiluminescence and Bioluminescence
Chapter 16: Miniaturized Analytical Devices Based on Chemiluminescence, Bioluminescence and Electrochemiluminescence
Published:28 Oct 2010
L. J. Kricka and J. Y. Park, in Chemiluminescence and Bioluminescence, ed. A. Roda, The Royal Society of Chemistry, 2010, ch. 16, pp. 543-556.
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Advances in miniaturization technology derived from the microelectronics industry have facilitated the miniaturization of analytical devices. The assays embedded within miniaturized analytical devices utilize a range of detection technologies including electrochemical, colorimetric, and a range of luminescence detection technologies based on fluorescence, chemiluminescence, bioluminescence, and electrochemiluminescence. This chapter reviews the basics of micro-miniature analytical devices (microchips, lab-on-a-chip or micro total analytical systems) and surveys microchip-based assays that utilize chemiluminescence, bioluminescence, and electrochemiluminescence as the detection technology.