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Drug Discovery
Synthetic Methods in Drug Discovery: Volume 1Check Access
Edited by
Paul Doyle
Paul Doyle
Peakdale Molecular Ltd, UK
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Volume
1
Hardback ISBN:
978-1-84973-803-3
PDF ISBN:
978-1-78262-208-6
EPUB ISBN:
978-1-78262-790-6
Special Collection:
2016 ebook collection
Series:
Drug Discovery Series
No. of Pages:
455
Published online:
15 Jul 2016
Published in print:
01 Aug 2016
Book Chapter
Chapter 10: New Frontiers with Transition Metals Check Access
By
Brian S. Gerstenberger
Brian S. Gerstenberger
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-
Published:15 Jul 2016
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Special Collection: 2016 ebook collectionSeries: Drug Discovery Series
Page range:
411 - 442
Citation
B. S. Gerstenberger, in Synthetic Methods in Drug Discovery: Volume 1, ed. D. C. Blakemore, P. M. Doyle, Y. M. Fobian, D. Blakemore, Y. Fobian, and P. Doyle, The Royal Society of Chemistry, 2016, vol. 1, ch. 10, pp. 411-442.
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Transition metals play a significant role in drug discovery due to their powerful abilities to affect synthetic transformations and construction a vast array of bond formations. This chapter highlights recent interesting transformations in the transition metal driven reactions. The pharmaceutical industry's use of transition metal catalysts has been dominated by palladium and copper metals, but the focus will be on the use and application of iron, nickel, and cobalt catalyst.
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