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SPR Amino Acids, Peptides and Proteins
Amino Acids, Peptides and Proteins: Volume 39Check Access
Edited by
Maxim Ryadnov;
Maxim Ryadnov
National Physical Laboratory, UK
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Etelka Farkas
Etelka Farkas
University of Debrecen, Hungary
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Volume
39
Hardback ISBN:
978-1-84973-982-5
PDF ISBN:
978-1-84973-996-2
EPUB ISBN:
978-1-78262-346-5
No. of Pages:
234
Published online:
01 Dec 2014
Published in print:
09 Dec 2014
Book Chapter
De novo designed metallopeptides Check Access
By
Anna F. A. Peacock
Anna F. A. Peacock
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Published:01 Dec 2014
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Page range:
148 - 191
Citation
E. Oheix and A. F. A. Peacock, in Amino Acids, Peptides and Proteins: Volume 39, ed. M. Ryadnov and E. Farkas, The Royal Society of Chemistry, 2014, vol. 39, pp. 148-191.
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The de novo design of miniature protein scaffolds, can be a powerful tool with which to answer important questions about protein structure and function. Similarly the design of metallopeptides de novo provides an opportunity to interrogate the role of the protein matrix in tuning the chemistries of coordinated metal ions. This chapter describes recent advances made in the field of de novo metallopeptide design, and covers a broad range of metal ion sites (both native and non-native) and protein scaffolds.
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