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Kinase Drug Discovery

Modern Approaches

Drug Discovery Series

Editor-in-chief

David Thurston, King's College, UK

Series editors:

David Fox, Vulpine Science and Learning, UK

Ana Martinez, Centro de Investigaciones Biologicas-CSIC, Spain

David Rotella, Montclair State University, USA

Hong Shen, Roche Innovation Center Shanghai, China

Editorial advisor:

Ian Storer, AstraZeneca, UK

Titles in the Series:

1: Metabolism, Pharmacokinetics and Toxicity of Functional Groups

2: Emerging Drugs and Targets for Alzheimer's Disease; Volume 1

3: Emerging Drugs and Targets for Alzheimer's Disease; Volume 2

4: Accounts in Drug Discovery

5: New Frontiers in Chemical Biology

6: Animal Models for Neurodegenerative Disease

7: Neurodegeneration

8: G Protein-Coupled Receptors

9: Pharmaceutical Process Development

10: Extracellular and Intracellular Signaling

11: New Synthetic Technologies in Medicinal Chemistry

12: New Horizons in Predictive Toxicology

13: Drug Design Strategies: Quantitative Approaches

14: Neglected Diseases and Drug Discovery

15: Biomedical Imaging

16: Pharmaceutical Salts and Cocrystals

17: Polyamine Drug Discovery

18: Proteinases as Drug Targets

19: Kinase Drug Discovery

20: Drug Design Strategies: Computational Techniques and Applications

21: Designing Multi-Target Drugs

22: Nanostructured Biomaterials for Overcoming Biological Barriers

23: Physico-Chemical and Computational Approaches to Drug Discovery

24: Biomarkers for Traumatic Brain Injury

25: Drug Discovery from Natural Products

26: Anti-Inflammatory Drug Discovery

27: New Therapeutic Strategies for Type 2 Diabetes: Small Molecules

28: Drug Discovery for Psychiatric Disorders

29: Organic Chemistry of Drug Degradation

30: Computational Approaches to Nuclear Receptors

31: Traditional Chinese Medicine

32: Successful Strategies for the Discovery of Antiviral Drugs

33: Comprehensive Biomarker Discovery and Validation for Clinical Application

34: Emerging Drugs and Targets for Parkinson's Disease

35: Pain Therapeutics; Current and Future Treatment Paradigms

36: Biotherapeutics: Recent Developments using Chemical and Molecular Biology

37: Inhibitors of Molecular Chaperones as Therapeutic Agents

38: Orphan Drugs and Rare Diseases

39: Ion Channel Drug Discovery

40: Macrocycles in Drug Discovery

41: Human-based Systems for Translational Research

42: Venoms to Drugs: Venom as a Source for the Development of Human Therapeutics

43: Carbohydrates in Drug Design and Discovery

44: Drug Discovery for Schizophrenia

45: Cardiovascular and Metabolic Disease: Scientific Discoveries and New Therapies

46: Green Chemistry Strategies for Drug Discovery

47: Fragment-Based Drug Discovery

48: Epigenetics for Drug Discovery

49: New Horizons in Predictive Drug Metabolism and Pharmacokinetics

50: Privileged Scaffolds in Medicinal Chemistry: Design, Synthesis, Evaluation

51: Nanomedicines: Design, Delivery and Detection

52: Synthetic Methods in Drug Discovery: Volume 1

53: Synthetic Methods in Drug Discovery: Volume 2

54: Drug Transporters: Role and Importance in ADME and Drug Development

55: Drug Transporters: Recent Advances and Emerging Technologies

56: Allosterism in Drug Discovery

57: Anti-aging Drugs: From Basic Research to Clinical Practice

58: Antibiotic Drug Discovery: New Targets and Molecular Entities

59: Peptide-based Drug Discovery: Challenges and New Therapeutics

60: Drug Discovery for Leishmaniasis

61: Biophysical Techniques in Drug Discovery

62: Acute Brain Impairment Through Stroke: Drug Discovery and Translational Research

63: Theranostics and Image Guided Drug Delivery

64: Pharmaceutical Formulation: The Science and Technology of Dosage Forms

65: Small-molecule Transcription Factor Inhibitors in Oncology

66: Therapies for Retinal Degeneration: Targeting Common Processes

67: Kinase Drug Discovery: Modern Approaches

How to obtain future titles on publication:

A standing order plan is available for this series. A standing order will bring delivery of each new volume immediately on publication.

For further information please contact:

Book Sales Department, Royal Society of Chemistry, Thomas Graham House, Science Park, Milton Road, Cambridge, CB4 0WF, UK

Telephone: +44 (0)1223 420066, Fax: +44 (0)1223 420247,

Visit our website at www.rsc.org/books

Kinase Drug Discovery

Modern Approaches

Edited by

Richard A. Ward

AstraZeneca, UK

and

Frederick W. Goldberg

AstraZeneca, UK

graphic

Drug Discovery Series No. 67

Print ISBN: 978-1-78801-083-2

PDF ISBN: 978-1-78801-309-3

EPUB ISBN: 978-1-78801-563-9

Print ISSN: 2041-3203

Electronic ISSN: 2041-3211

A catalogue record for this book is available from the British Library

© The Royal Society of Chemistry 2019

All rights reserved

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