Skip to Main Content
Skip Nav Destination

The asymmetric autocatalysis of pyrimidylalkanols is an extremely distinctive reaction that can induce significant asymmetric amplification in a simple self-replication reaction. As asymmetric amplification is the key to unraveling the mystery of homochirality, the mechanism of this reaction has attracted considerable attention over a long time. Numerous studies aimed at elucidating the mechanism of this reaction have revealed that the aggregation of zinc alkoxides plays an important role in asymmetric amplification. In this chapter, we introduce the various aggregation forms of pyrimidylalkanol zinc alkoxides, as revealed by single-crystal X-ray diffraction analysis, and discuss their relationship to other mechanistic studies, as well as the study of the equilibrium of aggregation states in solution by circular dichroism spectroscopy.

You do not currently have access to this chapter, but see below options to check access via your institution or sign in to purchase.
Don't already have an account? Register
Close Modal

or Create an Account

Close Modal
Close Modal