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Perfluoroalkyl Substances
Edited by
Bruno Améduri
Bruno Améduri
Institut Charles Gerhardt, France
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Hardback ISBN:
978-1-83916-568-9
PDF ISBN:
978-1-83916-759-1
EPUB ISBN:
978-1-83916-760-7
Special Collection:
2022 ebook collection
No. of Pages:
634
Publication date:
15 Aug 2022
Book Chapter
CHAPTER 10: Perfluoroalkylated Biomolecules for Medicinal Chemistry and Biological Studies
By
T. Brigaud
;
T. Brigaud
CY Cergy Paris Université, CNRS, BioCIS
95000 Cergy Pontoise
France
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T. Lequeux
T. Lequeux
Normandie Université, Laboratoire de Chimie Moléculaire et Thioorganique, LCMT UMR 6507, ENSICAEN, UNICAEN, CNRS
14032 Caen
France
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Published:15 Aug 2022
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Special Collection: 2022 ebook collection
Page range:
459 - 476
Citation
T. Brigaud, B. Crousse, and T. Lequeux, in Perfluoroalkyl Substances, ed. B. Améduri, The Royal Society of Chemistry, 2022, pp. 459-476.
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For many years, it has been well established that the presence of a fluorine atom and/or a fluorinated group in molecules leads to active and selective drugs for certain diseases. With developments in this field, polyfluoroalkylated compounds for nuclear magnetic resonance (19F NMR) spectroscopy and magnetic resonance imaging (19F MRI) have been intensively studied in chemical biological investigations, imaging and diagnostics.
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