Chapter 3: Blood VOC Biomarkers Check Access

Blood can be considered a primary reservoir of volatile organic compounds (VOCs) secreted by different tissues and organs as well as produced by blood biochemistry. This chapter presents a concise, although admittedly nonexhaustive, didactic presentation of some of the main concepts and approaches related to blood volatilomics. It attempts to review the source and characteristics of volatilomics through the VOCs emanating from infected cells and their microenvironment to the blood. It also presents and discusses the exchange of VOCs with several body fluids, including the cellular environment, tissues, breath, etc. Application of blood VOCs in human health is presented and discussed.