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Adaptive and biocompatible technologies are highly required in health applications, including point-of-care and wearable devices for monitoring volatile biomarkers. The current chapter introduces adaptive technologies that occur at the device level, such as self-healing, flexibility and stretchability but also those that take place on the control system related to signal processing and multivariate analysis of VOCs data. The chapter also discusses biocompatible materials and their implementation as collection kits for volatile organic compounds (VOCs) and related sensing devices.

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