Chapter 9: Signal Transfer and Transduction between Cells Check Access

Cell-to-cell communication has a critical role during tumor development and progression, allowing cancer cells to reprogram not only the surrounding tumor microenvironment, but also cells located at distant sites. This chapter focuses on the potential role of volatile organic compounds (VOCs) as signaling/communication agents that exchange over relatively long distances between cells and/or from one cell to another destination. The chapter also discusses VOC signaling as an alternative and/or complementary perspective to proteomic and genomic approaches in monitoring cancer development.