Chapter 6: Saliva and Related Specimens as a Source of Volatile Biomarkers Check Access

This chapter contains general information about saliva and related specimens, like sputum, in relation to volatile organic compounds (VOCs). Characteristics of the matrix, its functions and composition are described. A comprehensive list of VOCs emanating from saliva and salivary bacteria are included. Different methods employed for salivary VOC sample preparation and preconcentration, as well as conditions of collection and storage of oral fluid, are thoroughly described. Finally, statistical and chemometric approaches used by other researchers have been compared.