Chalcogen Chemistry: Fundamentals and Applications
Chapter 9: Optically Active Derivatives with a Stereogenic Sulfur Center: Synthesis and Applications
Published:15 Feb 2023
Dorota Krasowska, Agata. J. Pacuła-miszewska, Jacek Ścianowski, Jozef Drabowicz, 2023. "Optically Active Derivatives with a Stereogenic Sulfur Center: Synthesis and Applications", Chalcogen Chemistry: Fundamentals and Applications, Vito Lippolis, Claudio Santi, Eder J. Lenardão, Antonio L. Braga
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The preparation of optically active, especially enantiomerically pure, organic molecules is a challenging topic in chemistry. This issue has attracted widespread attention and has been studied for decades. Among these molecules there are a large number of sulfur-containing derivatives whose chirality results from the presence of a stereogenic sulfur atom with different valence and coordination numbers. Recently, they have gained great interest as biologically active compounds, components of new materials, as well as reagents, catalysts, and/or auxiliary agents that can be used effectively in asymmetric synthesis. This chapter is devoted to the presentation of the main groups of optically active sulfur derivatives and the most common approaches that have made it possible to isolate them as optically active forms and their selected synthetic applications.