Chapter 15: Nanofiber-based Systems

Nanofibers have become one of the most important bioactive delivery systems since they have high surface area and high porosity, and are considered safe. Phase separation, self-assembly, sol–gel methods, interfacial polymerization and electrospinning are commonly used for nanofiber fabrication. Among these methods, electrospinning surpasses the other methods in terms of efficiency and has emerged as the most efficacious technique for producing nanofibers. This chapter describes the structural composition, physicochemical properties, adhesion mechanism, modification methods, advantages and disadvantages and application scope of nanofiber-based bioactive delivery systems.