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Metal–organic frameworks (MOFs) are now being considered as the most promising materials within the class of coordination polymers. In recent years, many studies have presented MOFs as a class of organic–inorganic hybrid compounds that can be used as supports for the development of multifunctional materials. Nanocomposites have been receiving increasing attention due to the simplicity and versatility of the synthetic approach as well as the incorporation of properties of the single components and synergistic relations, achieving a vast area of science and technology The applications of MOF nanocomposites such as biological applications, sensing, adsorption, catalysis and extraction have been presented in this chapter. We have highlighted some already-studied applications and discussed the advantages and disadvantages of using MOF nanocomposites compared to other conventional or less traditional procedures, emphasizing the properties that influence their potential applications.

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