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Organophosphorus chemistry is a broad and exciting field, with potential opportunities for researchers involved in multi-disciplinary areas of scientific endeavour, including organic, medicinal, pharmaceutical, agricultural, and industrial chemistry. Organophosphorus compounds find extensive applications in all these fields owing to their inherent physical and biological properties. Since its first development in the 90s, green and sustainable chemistry has grown considerably over the past two decades. It has become much more prevalent among researchers working in all branches of chemical science. As part of these noteworthy developments, synthetic organic chemists have been motivated to develop eco-friendly methodologies for generating phosphorus-functionalised compounds of potential interest, focusing on various green chemistry principles. As a result, considerable progress towards green and sustainable chemistry has been accomplished during the last decade. In continuation of our earlier contributions, this chapter also aims to offer an overview of such developments in green synthetic approaches in organophosphorus chemistry reported in 2021.

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