Field-effect Transistor Biosensors for Rapid Pathogen Detection
Looking to prevent future outbreaks of deadly pathogens by early detection? Infectious diseases continue to be a challenge that necessitates increased precision in detection and integration to achieve accurate diagnosis at the point of care (PoC). Field-effect transistors (FETs) have been investigated widely as biosensors for pathogen detection, with advantages such as label-free and real-time detection capabilities. These biosensors have:
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a high level of sensitivity,
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a remarkable capacity for miniaturization,
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a molecular minimum limit of detection (LoD), and
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seamless integration with semiconductor technology
In this title, we have invited expert scientific researchers to share their experience in this field. This book focuses on the application and possibility of FETs as biosensors, for rapid and real time detection of pathogens that affect human life. The lack of commercially available efficient devices that can be deployed for this task resulted in the recent global spread of the SARS-CoV-19 virus. The book is an attempt to keep interested parties up to date.
Aimed at scientists and engineers (researchers, academics, and postgraduate students) who are interested in developing and using BioFET based sensors, the information in this book is crucial to help prevent future outbreaks of pathogens which bring with them significant impacts on human health and wellbeing.
Field-effect Transistor Biosensors for Rapid Pathogen Detection, Royal Society of Chemistry, 2024.
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Table of contents
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Part I: Introduction to Biologically Sensitive Field-effect Transistors (BioFETs)
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Chapter 1: The Physics and Operating Principles of Field-effect Transistor-based Biosensorsp1-27ByM. F. Mohd Razip Wee;M. F. Mohd Razip WeeaInstitute of Microengineering and Nanoelectronics (IMEN), Universiti Kebangsaan Malaysia 43600 UKM Bangi, Selangor, MalaysiaSearch for other works by this author on:Naif H. Al-Hardan;Naif H. Al-HardanbDepartment of Applied Physics, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor, MalaysiaSearch for other works by this author on:Asad Masood;Asad MasoodcSchool of Energy and Chemical Engineering, Xiamen University Malaysia, 43900 Sepang, Selangor, MalaysiaSearch for other works by this author on:Muhammed Azmi Abdul Hamid;Muhammed Azmi Abdul HamidbDepartment of Applied Physics, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor, MalaysiaSearch for other works by this author on:Azman Jalar;Azman JalarbDepartment of Applied Physics, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor, MalaysiaSearch for other works by this author on:Naser M. AhmedNaser M. AhmeddSchool of Physics, Universiti Sains Malaysia, 11800 Penang, MalaysiaSearch for other works by this author on:
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Chapter 2: Electrolyte-gated FET Biosensorsp28-72ByB. PiroB. PiroITODYS, CNRS, Université Paris Cité, Paris, FranceSearch for other works by this author on:
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Chapter 3: Challenges in the Detection of Emerging Novel Pathogens and Evolving Known Pathogensp73-92ByN. A. Shamsusah;N. A. ShamsusahaUniversiti Kebangsaan Malaysia, Department of Earth Sciences and Environment, Bangi, 43600, MalaysiaSearch for other works by this author on:M. E. I. Mohd Fadli;M. E. I. Mohd FadlibUniversiti Kebangsaan Malaysia, Department of Chemical Sciences, Bangi, 43600, MalaysiaSearch for other works by this author on:R. Emrizal;R. EmrizalcUniversiti Kebangsaan Malaysia, Department of Applied Physics, Bangi, 43600, MalaysiaSearch for other works by this author on:S. A. Hanifah;S. A. HanifahbUniversiti Kebangsaan Malaysia, Department of Chemical Sciences, Bangi, 43600, MalaysiaSearch for other works by this author on:M. Firdaus-RaihM. Firdaus-RaihcUniversiti Kebangsaan Malaysia, Department of Applied Physics, Bangi, 43600, MalaysiaSearch for other works by this author on:
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Part II: Real-time Detection – the Employment of BioFETs
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Chapter 4: Rapid Detection of Microorganisms Based on FET Devicesp93-126BySushant Sharma;Sushant SharmaaDepartment of Chemistry, Indian Institute of Technology Guwahati, Guwahati-781039, Assam, IndiaSearch for other works by this author on:Mayur Jagdishbhai Patel;Mayur Jagdishbhai PatelaDepartment of Chemistry, Indian Institute of Technology Guwahati, Guwahati-781039, Assam, IndiaSearch for other works by this author on:Ramkrishna Das Adhikari;Ramkrishna Das AdhikaribCentre for Nanotechnology and School for Health Science and Technology, Indian Institute of Technology Guwahati, Guwahati-781039, Assam, IndiaSearch for other works by this author on:Mizanur Alam;Mizanur AlambCentre for Nanotechnology and School for Health Science and Technology, Indian Institute of Technology Guwahati, Guwahati-781039, Assam, IndiaSearch for other works by this author on:Himangshu Baishya;Himangshu BaishyabCentre for Nanotechnology and School for Health Science and Technology, Indian Institute of Technology Guwahati, Guwahati-781039, Assam, IndiaSearch for other works by this author on:Deepak Yadav;Deepak YadavaDepartment of Chemistry, Indian Institute of Technology Guwahati, Guwahati-781039, Assam, IndiaSearch for other works by this author on:Manab Kalita;Manab KalitaaDepartment of Chemistry, Indian Institute of Technology Guwahati, Guwahati-781039, Assam, IndiaSearch for other works by this author on:Dheeraj Khubchandani;Dheeraj KhubchandaniaDepartment of Chemistry, Indian Institute of Technology Guwahati, Guwahati-781039, Assam, IndiaSearch for other works by this author on:Parameswar Krishnan IyerParameswar Krishnan IyeraDepartment of Chemistry, Indian Institute of Technology Guwahati, Guwahati-781039, Assam, IndiabCentre for Nanotechnology and School for Health Science and Technology, Indian Institute of Technology Guwahati, Guwahati-781039, Assam, IndiaSearch for other works by this author on:
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Chapter 5: Field-effect Transistor Biosensors Based on Nanomaterials for Zoonotic Pathogen Detectionp127-153ByFaiza Yahia;Faiza YahiaaChongqing Key Laboratory of Multi-scale Manufacturing Technology, Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Chongqing, People’s Republic of ChinabChongqing School, University of Chinese Academy of Sciences, Chongqing 400714, ChinacUniversity of Chinese Academy of Sciences, Beijing 100049, ChinaSearch for other works by this author on:Farah Nasri;Farah NasridLaboratory of Electronics and Micro-Electronics (EμE) FSM, University of Monastir, Monastir, TunisiaSearch for other works by this author on:Lyes Douadji;Lyes DouadjiaChongqing Key Laboratory of Multi-scale Manufacturing Technology, Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Chongqing, People’s Republic of ChinabChongqing School, University of Chinese Academy of Sciences, Chongqing 400714, ChinaSearch for other works by this author on:Atef Thamri;Atef ThamrieCRMN, Centre for Research on Microelectronics and Nanotechnology of Sousse, NANOMISENE Lab, LR16CRMN01, Code Postal 4050, Sousse, TunisiaSearch for other works by this author on:Deqiang Wang;Deqiang WangaChongqing Key Laboratory of Multi-scale Manufacturing Technology, Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Chongqing, People’s Republic of ChinabChongqing School, University of Chinese Academy of Sciences, Chongqing 400714, ChinaSearch for other works by this author on:Chaker TliliChaker TliliaChongqing Key Laboratory of Multi-scale Manufacturing Technology, Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Chongqing, People’s Republic of ChinabChongqing School, University of Chinese Academy of Sciences, Chongqing 400714, ChinaSearch for other works by this author on:
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Chapter 6: Field-effect Transistor Biosensors for Rapid SARS-CoV-2 Detectionp154-194ByA. Ibijbijen;A. IbijbijenParis-Saclay University, ICMMO, UMR CNRS, Site Henri-Moissan, 17 Avenue des sciences, 91405, Orsay FranceSearch for other works by this author on:F. Besbes;F. BesbesParis-Saclay University, ICMMO, UMR CNRS, Site Henri-Moissan, 17 Avenue des sciences, 91405, Orsay FranceSearch for other works by this author on:H. Korri-YoussoufiH. Korri-YoussoufiParis-Saclay University, ICMMO, UMR CNRS, Site Henri-Moissan, 17 Avenue des sciences, 91405, Orsay FranceSearch for other works by this author on:
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Chapter 7: The Future of Commercializing FET-based Biosensorsp195-223ByH. Ben Halima;H. Ben HalimaaUniversity Bourgogne-Franche-Comte, UTINAM Institute, 25030 Besancon Cedex, FranceSearch for other works by this author on:A. Errachid;A. ErrachidbUniversity of Lyon, Institute of Analytical Sciences, 69100 Villeurbanne, FranceSearch for other works by this author on:N. Jaffrezic-RenaultN. Jaffrezic-RenaultbUniversity of Lyon, Institute of Analytical Sciences, 69100 Villeurbanne, FranceSearch for other works by this author on:
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