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Detection Science
Lab-on-a-chip Devices for Advanced Biomedicines: Laboratory Scale Engineering to Clinical Ecosystem
Edited by
Arpana Parihar;
Arpana Parihar
CSIR-Advanced Materials and Processes Research Institute, India
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Piyush Pradeep Mehta
Piyush Pradeep Mehta
Cipla R & D, India
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Volume
25
Hardback ISBN:
978-1-83767-237-0
PDF ISBN:
978-1-83767-347-6
EPUB ISBN:
978-1-83767-348-3
Special Collection:
2024 eBook Collection
Series:
Detection Science
No. of Pages:
695
Publication date:
14 Aug 2024
About this book
The global miniature devices market is poised to surpass a valuation of $12–$15 billion USD by the year 2030. Lab-on-a-chip (LOC) devices are a vital component of this market.
Comprising a network of microchannels, electrical circuits, sensors, and electrodes, LOC is a miniaturized integrated device platform used to streamline day-to-day laboratory functions, run cost-effective clinical analyses and curb the need for centralized instrumentation facilities in remote areas. Compact design, portability, ease of operation, low sample volume, short reaction time, and parallel investigation stand as the pivotal factors driving the widespread acceptance of LOC within the biomedical community.
In this book, the Editors meticulously explore LOC through three key ‘Ts’:
Theories (microfluidics, microarrays, instrumentation, software);
Technologies (additive manufacturing, artificial intelligence, computational thinking, smart consumables, scale-up tactics, and biofouling); and
Trends (biomedical analysis, point-of-care diagnostics, personalized healthcare, bioactive synthesis, disease diagnosis, and space applications)
This comprehensive text not only provides readers with a thorough understanding of the current advancements in the LOC domain but also offers valuable insights to support the utilization of miniaturized devices for enhanced healthcare practices. Aimed at career researchers looking for instruction in the topic and newcomers to the area, the book is also useful for undergraduate and postgraduate students embarking on new studies or for those interested in reading about the LOC platform.
Lab-on-a-chip Devices for Advanced Biomedicines: Laboratory Scale Engineering to Clinical Ecosystem, Royal Society of Chemistry, 2024.
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Digital access
$235.00
Print format
Lab-on-Chip Devices for Advanced Biomedicines
$275.00
Table of contents
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Chapter 1: Lab-on-a-chip – Reform, Perform, and Transformp1-32ByArpana Parihar;Arpana Parihara Department of Translational Medicine, All India Institute of Medical Sciences, Saket Nagar, Bhopal 462020, Madhya Pradesh, India [email protected]Search for other works by this author on:Vedika Khare;Vedika Khareb Michigan Technological University, Houghton 49931, Michigan, USASearch for other works by this author on:Mayank GargMayank Gargc Department of Biomedical Engineering, Texas A&M University, College Station, Texas, USASearch for other works by this author on:
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Chapter 2: Lab-on-a-chip: A Road Map of Silicon Chemistry to Multipurpose Microfluidic Chipsp33-72ByNeshat Askarzadeh;Neshat Askarzadeha Faculty of New Sciences and Technologies, Department of Life Science Engineering, University of Tehran, Tehran, 1439957131 IranSearch for other works by this author on:Javad Mohammadi;Javad Mohammadia Faculty of New Sciences and Technologies, Department of Life Science Engineering, University of Tehran, Tehran, 1439957131 IranSearch for other works by this author on:Hodjattallah Rabbani;Hodjattallah Rabbanib Medical Genetics Department, Institute of Medical Biotechnology (IMB), National Institute of Genetic Engineering and Biotechnology (NIGEB), Tehran, IranSearch for other works by this author on:Morteza HosseiniMorteza Hosseinia Faculty of New Sciences and Technologies, Department of Life Science Engineering, University of Tehran, Tehran, 1439957131 Iran [email protected]Search for other works by this author on:
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Chapter 3: Lab-on-a-chip: Fabrication and Frontiers Aiming at Biomedicinesp73-137ByTanvir Ahmed;Tanvir Ahmeda Department of Pharmaceutical Sciences, School of Health and Life Sciences, North South University, Plot 15, Block B, Bashundhara R/A, Dhaka 1229, Bangladesh [email protected]Search for other works by this author on:Zarin Tasnim TishaZarin Tasnim Tishab School of Pharmacy, BRAC University, Kha 224 Bir Uttam Rafiqul Islam Avenue, Merul Badda, Dhaka 1212, BangladeshSearch for other works by this author on:
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Chapter 4: Lab-on-a-chip: Summary of 3D/4D Printed Biochipsp138-157ByArpana Agrawal;Arpana Agrawala Department of Physics, Shri Neelkantheshwar Government Post-Graduate College, Khandwa 450001, India [email protected]Search for other works by this author on:C. M. HussainC. M. Hussainb Department of Chemistry and Environmental Science, New Jersey Institute of Technology, USASearch for other works by this author on:
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Chapter 5: Lab-on-a-chip: A Novel Platform for Disease Diagnosisp158-189ByReetu Rani;Reetu Rania International Research Organization for Advanced Science and Technology, Kumamoto University, Kumamoto, JapanSearch for other works by this author on:Manasi Esther Jinugu;Manasi Esther Jinugub Department of Chemical Engineering, Indian Institute of Technology (IIT) Gandhinagar, Palaj, Gujarat, IndiaSearch for other works by this author on:Pratibha Gangwar;Pratibha Gangwarc Indian Institute of Technology Ropar, Punjab, IndiaSearch for other works by this author on:Prachi Thareja;Prachi Tharejab Department of Chemical Engineering, Indian Institute of Technology (IIT) Gandhinagar, Palaj, Gujarat, IndiaSearch for other works by this author on:Arpana Parihar;Arpana Parihard Industrial Waste Utilization, Nano and Biomaterials, Department of Translational Medicine, All India Institute of Medical Sciences, Saket Nagar, Bhopal, Madhya Pradesh, IndiaSearch for other works by this author on:Mayank GargMayank Garge Department of Biomedical Engineering, Texas A&M University, College Station, Texas, USA [email protected]Search for other works by this author on:
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Chapter 6: Role of Microfluidics in Drug Encapsulation for Point-of-care Diagnosis and Prognosisp190-220BySarita Mishra;Sarita Mishraa CSIR—Institute of Genomics and Integrative Biology, Mathura Road, New Delhi 110025, IndiaSearch for other works by this author on:Sekar Harikrishnan;Sekar Harikrishnanb Minerals, Energy and Chemical Engineering, Curtin University, Bentley Campus, Perth, Western Australia, AustraliaSearch for other works by this author on:Ahmad Perwez;Ahmad Perwezc Case Comprehensive Cancer Centre, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44016, USASearch for other works by this author on:Khushnuma Wahabi;Khushnuma Wahabid Genome Biology Laboratory, Department of Biosciences, Jamia Millia Islamia, New Delhi 110025, IndiaSearch for other works by this author on:Ujjwal Ranjan Dahiya;Ujjwal Ranjan Dahiyae Centre for Biomedical Engineering, Indian Institute of Technology, New Delhi 110016, India [email protected]Search for other works by this author on:Subia BanoSubia Banof Department of Biotechnology, Indian Institute of Technology Kharagpur, Kharagpur 721302, India [email protected]Search for other works by this author on:
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Chapter 7: Lab-on-a-chip: A Stepping Stone for Personalized Healthcare Managementp221-243ByCansu İlke Kuru;Cansu İlke Kurua Graduate School of Natural and Applied Sciences, Department of Biotechnology, Ege University, 35040, İzmir, Turkeyb Buca Municipality Buca Science and Art Center, 35390, Izmir, TurkeySearch for other works by this author on:Fulden Ulucan-KarnakFulden Ulucan-Karnakc Institute of Health Sciences, Medical Biochemistry Department, Ege University, 35040, Bornova, Izmir, Turkey [email protected]Search for other works by this author on:
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Chapter 8: Lab-on-a-chip for In Vitro Diagnosis: Manipulating the Power of Nanoparticlesp244-271ByZouhair Ait-Touchente;Zouhair Ait-Touchentea Université Claude Bernard Lyon-1, ISA, UMR 5280, CNRS, 5 Rue de la Doua, 69100 Villeurbanne, Franceb Université Claude Bernard Lyon-1, CNRS, LAGEPP UMR 5007, 69100 Villeurbanne, FranceSearch for other works by this author on:Sumera Khizar;Sumera Khizara Université Claude Bernard Lyon-1, ISA, UMR 5280, CNRS, 5 Rue de la Doua, 69100 Villeurbanne, FranceSearch for other works by this author on:Nadia Zine;Nadia Zinea Université Claude Bernard Lyon-1, ISA, UMR 5280, CNRS, 5 Rue de la Doua, 69100 Villeurbanne, FranceSearch for other works by this author on:Nicole Jaffrezic-Renault;Nicole Jaffrezic-Renaulta Université Claude Bernard Lyon-1, ISA, UMR 5280, CNRS, 5 Rue de la Doua, 69100 Villeurbanne, FranceSearch for other works by this author on:Abdelhamid Errachid;Abdelhamid Errachida Université Claude Bernard Lyon-1, ISA, UMR 5280, CNRS, 5 Rue de la Doua, 69100 Villeurbanne, FranceSearch for other works by this author on:Abdelhamid ElaissariAbdelhamid Elaissaria Université Claude Bernard Lyon-1, ISA, UMR 5280, CNRS, 5 Rue de la Doua, 69100 Villeurbanne, France [email protected]Search for other works by this author on:
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Chapter 9: Integration of Artificial Intelligence and Computational Thinking in Lab-on-a-chip Technology for Quality Improvement in Healthcarep272-309BySuparna Das;Suparna Dasa Computer Science and Engineering, BVRIT HYDERABAD College of Engineering for Women, Hyderabad, IndiaSearch for other works by this author on:Hirak MazumdarHirak Mazumdarb Department of Computer Science and Engineering, Graphic Era Deemed to be University, Dehradun, Uttarakhand, India [email protected]Search for other works by this author on:
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Chapter 10: Lab-on-a-chip: An Emerging Analytical Tool for Drug Testingp310-341ByP. Sarbadhikary;P. SarbadhikaryLaser Research Centre, Faculty of Health Sciences, University of Johannesburg, PO Box 17011, Doornfontein 2028, South Africa [email protected]Search for other works by this author on:K. A. Olofinsan;K. A. OlofinsanLaser Research Centre, Faculty of Health Sciences, University of Johannesburg, PO Box 17011, Doornfontein 2028, South AfricaSearch for other works by this author on:B. P. GeorgeB. P. GeorgeLaser Research Centre, Faculty of Health Sciences, University of Johannesburg, PO Box 17011, Doornfontein 2028, South AfricaSearch for other works by this author on:
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Chapter 11: Lab-on-a-chip: Efficient Preparation of Bioactive Compounds Using On-chip Flow Synthesisp342-361ByIngrid Cavalcanti Chipoline;Ingrid Cavalcanti Chipolinea LaSOPB, Chemical Organic Department, Federal University of Rio de Janeiro, Rio de Janeiro, Brazilb LABECFAR, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, BrazilSearch for other works by this author on:Pedro Henrique Oliveira Borges;Pedro Henrique Oliveira Borgesa LaSOPB, Chemical Organic Department, Federal University of Rio de Janeiro, Rio de Janeiro, Brazilb LABECFAR, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, BrazilSearch for other works by this author on:Sabrina Baptista Ferreira;Sabrina Baptista Ferreiraa LaSOPB, Chemical Organic Department, Federal University of Rio de Janeiro, Rio de Janeiro, BrazilSearch for other works by this author on:Floriano Paes Silva JuniorFloriano Paes Silva Juniorb LABECFAR, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil [email protected]Search for other works by this author on:
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Chapter 12: DIY Lab-on-a-chip Platforms: A Solution for Simple Nucleic Acid-based Assays in the Absence of Proper (Chip) Facilitiesp362-401ByP. ChaumplukP. ChaumplukDepartment of Botany, Chulalongkorn University, Phayathai, Bangkok 10330, Thailand [email protected]Search for other works by this author on:
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Chapter 13: When Earth Is Not Enough: Lab-on-a-chip Accelerating Space Researchp402-429ByA. KrakosA. KrakosDepartment of Microsystems, Faculty of Electronics, Photonics and Microsystems, Wroclaw University of Science and Technology, Janiszewskiego 11/17, 50-372 Wroclaw, Poland [email protected]Search for other works by this author on:
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Chapter 14: Lab-on-a-chip: Mechanism and Mitigation of Biofoulingp430-460ByArchita Sharma;Archita Sharmaa Department of Biomedical Engineering, Texas A&M University, College Station, Texas, USA**Search for other works by this author on:Ritika Modi;Ritika Modib Department of Food Science and Technology, Texas A&M University, College Station, Texas, USA**Search for other works by this author on:Arpana Parihar;Arpana Pariharc Industrial Waste Utilization, Nano and Biomaterials, Department of Translational Medicine, All India Institute of Medical Sciences, Saket Nagar, Bhopal, Madhya Pradesh, IndiaSearch for other works by this author on:Mayank GargMayank Garga Department of Biomedical Engineering, Texas A&M University, College Station, Texas, USA [email protected]Search for other works by this author on:
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Chapter 15: Organ-on-a-chip Technology Roadmap: Regulatory Framework, Industry Adoption, Key Players, Technology Transfer, Validation, and Ethical Considerationsp461-504BySimone BonaccorsiSimone BonaccorsiAstraZeneca, Pepparedsleden 1, 431 83 Mölndal, Sweden [email protected]Search for other works by this author on:
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Chapter 16: Lab-on-a-chip: From Prototyping to Scale-up Productionp505-559ByAllen Mathew;Allen Mathewa School of Mechanical and Materials Engineering, University College Dublin, Belfield, Dublin 4, IrelandSearch for other works by this author on:Dongsheng Liu;Dongsheng Liua School of Mechanical and Materials Engineering, University College Dublin, Belfield, Dublin 4, IrelandSearch for other works by this author on:Mingzhi Yu;Mingzhi Yua School of Mechanical and Materials Engineering, University College Dublin, Belfield, Dublin 4, IrelandSearch for other works by this author on:Pieter Haasbroek;Pieter Haasbroekb School of Engineering, Institute of Polymer Nanotechnology, FHNW University of Applied Sciences and Arts Northwestern Switzerland, Klosterzelgstrasse 2, CH-5210 Windisch, SwitzerlandSearch for other works by this author on:Xinhui Wang;Xinhui Wanga School of Mechanical and Materials Engineering, University College Dublin, Belfield, Dublin 4, IrelandSearch for other works by this author on:Tianyu Guan;Tianyu Guana School of Mechanical and Materials Engineering, University College Dublin, Belfield, Dublin 4, IrelandSearch for other works by this author on:Sana Zaki;Sana Zakia School of Mechanical and Materials Engineering, University College Dublin, Belfield, Dublin 4, IrelandSearch for other works by this author on:Quanliang Su;Quanliang Sua School of Mechanical and Materials Engineering, University College Dublin, Belfield, Dublin 4, IrelandSearch for other works by this author on:Jiaqi Li;Jiaqi Lia School of Mechanical and Materials Engineering, University College Dublin, Belfield, Dublin 4, IrelandSearch for other works by this author on:Akshaya Jagannath;Akshaya Jagannatha School of Mechanical and Materials Engineering, University College Dublin, Belfield, Dublin 4, IrelandSearch for other works by this author on:Yixin Chen;Yixin Chena School of Mechanical and Materials Engineering, University College Dublin, Belfield, Dublin 4, IrelandSearch for other works by this author on:Per Magnus Kristiansen;Per Magnus Kristiansena School of Mechanical and Materials Engineering, University College Dublin, Belfield, Dublin 4, Irelandb School of Engineering, Institute of Polymer Nanotechnology, FHNW University of Applied Sciences and Arts Northwestern Switzerland, Klosterzelgstrasse 2, CH-5210 Windisch, SwitzerlandSearch for other works by this author on:Nan ZhangNan Zhanga School of Mechanical and Materials Engineering, University College Dublin, Belfield, Dublin 4, Ireland [email protected]Search for other works by this author on:
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Chapter 17: Lab-on-a-chip: Unit Operations to Scale-up Strategiesp560-614ByDanial Khorsandi;Danial Khorsandia Terasaki Institute for Biomedical Innovation, Los Angeles, CA, 90064, USA [email protected]Search for other works by this author on:Jia-Wei Yang;Jia-Wei Yanga Terasaki Institute for Biomedical Innovation, Los Angeles, CA, 90064, USASearch for other works by this author on:Serena Jenson;Serena Jensonb Department of Biological Sciences, California Polytechnic State University, San Luis Obispo, CA, 93407, USASearch for other works by this author on:Takamaro Kajino;Takamaro Kajinoc Department of Biological Chemistry, University of Michigan, Ann Arbor, MI, 48109, USASearch for other works by this author on:Surjendu Maity;Surjendu Maitya Terasaki Institute for Biomedical Innovation, Los Angeles, CA, 90064, USASearch for other works by this author on:Abdul Rahim Chethikkattuveli Salih;Abdul Rahim Chethikkattuveli Saliha Terasaki Institute for Biomedical Innovation, Los Angeles, CA, 90064, USASearch for other works by this author on:Vadim Jucaud;Vadim Jucauda Terasaki Institute for Biomedical Innovation, Los Angeles, CA, 90064, USASearch for other works by this author on:Mehmet R. DokmeciMehmet R. Dokmecia Terasaki Institute for Biomedical Innovation, Los Angeles, CA, 90064, USASearch for other works by this author on:
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Chapter 18: Miniaturized Devices: A Silk Route for Innovative Commercial Prospectsp615-648ByPiyush Pradeep MehtaPiyush Pradeep MehtaCipla R&D, LBS Road, Vikhroli (W), Mumbai, Maharashtra, 400083, India [email protected]Search for other works by this author on:
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