Cardiovascular Nanomedicine
The integration of nanoparticles with classical drugs to create biocompatible delivery platforms for the treatment of cardiovascular diseases can make a major impact on patient welfare.
Traditional drug delivery systems are not selective and induce severe collateral damage to surrounding non-diseased cells and tissues. Nanoparticles, however, can be bio-conjugated with antibodies to encapsulate cardiovascular drugs, gaseous molecules and biomolecules to selectively deliver them in a safe, targeted and cost-effective manner.
This book provides in-depth and insightful discussion on the mechanistic, pre-clinical and clinical applications of nanomedicine in cardiovascular disease. It not only discusses core chemical concepts via the synthesis of novel nanotechnology-based drug formulations, but also covers the latest drug delivery advances including innovative therapeutic targets in cardiovascular lesions at an early, curable and reversible stage.
Written by experts in the field, students and researchers will find this book equally useful for understanding the trends and challenges of the clinical translation of cardiovascular nanomedicine.
Cardiovascular Nanomedicine, Royal Society of Chemistry, 2024.
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Table of contents
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Chapter 1: Cardiovascular Nanomedicine: From Targeted Delivery to Theranosticsp1-18ByMaryam Rezvani;Maryam RezvaniaDepartment of Life and Environmental Sciences, Drug Science Division, University of Cagliari,09124 Cagliari,ItalybAdvanced Nanobiotechnology and Nanomedicine Research Group (ANNRG), Iran University of Medical Sciences,Tehran,IranE-mail: [email protected]Search for other works by this author on:Nejat DüzgüneşNejat DüzgüneşcDepartment of Biomedical Sciences, Arthur A. Dugoni School of Dentistry, University of the Pacific,San Francisco, CA 94103,USASearch for other works by this author on:
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Chapter 2: Photoluminescent Nanomaterials for Cardiovascular Diagnosis and Therapeuticsp19-46BySílvia Rodrigues Gavinho;Sílvia Rodrigues Gavinhoai3N and Physics Department, Aveiro University,3800-193 Aveiro,PortugalSearch for other works by this author on:Suresh Kumar Jakka;Suresh Kumar Jakkaai3N and Physics Department, Aveiro University,3800-193 Aveiro,PortugalSearch for other works by this author on:Pavani Krishnapuram;Pavani Krishnapuramai3N and Physics Department, Aveiro University,3800-193 Aveiro,PortugalSearch for other works by this author on:Ujjawal Sharma;Ujjawal SharmabSchool of Health Science, Central University of Punjab,IndiaSearch for other works by this author on:Vallamkondu Jayalakshmi;Vallamkondu JayalakshmicNational Institute of Technology Warangal,IndiaSearch for other works by this author on:Manuel Pedro Fernandes GraçaManuel Pedro Fernandes GraçaSearch for other works by this author on:
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Chapter 3: Nanoparticles for the Treatment of Ischemic Heart Diseasesp47-87ByFatiha Benslimane;Fatiha BenslimaneaBiomedical Research Center, Qatar University,2713 Doha,QatarSearch for other works by this author on:Zain Zaki Salim ZakariaZain Zaki Salim ZakariaaBiomedical Research Center, Qatar University,2713 Doha,QatarbDepartment of Biomedical Sciences, College of Health Sciences, QU-Health, Qatar University,2713 Doha,QatarSearch for other works by this author on:
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Chapter 4: Cardiovascular Nanomedicine: Mode of Action and Applicationsp88-109ByFouzia Perveen Malik;Fouzia Perveen MalikaSchool of Interdisciplinary Engineering and Sciences (SINES), NUST, H-12,Islamabad 44000,PakistanE-mail: [email protected]Search for other works by this author on:Sumaiya Azam;Sumaiya AzamaSchool of Interdisciplinary Engineering and Sciences (SINES), NUST, H-12,Islamabad 44000,PakistanSearch for other works by this author on:Aqsa Aleem;Aqsa AleemaSchool of Interdisciplinary Engineering and Sciences (SINES), NUST, H-12,Islamabad 44000,PakistanSearch for other works by this author on:Jahanzaib NowsherwanJahanzaib NowsherwanbInorganic Chemistry Department, Department of Chemistry, University of Oxford,Oxford,UKSearch for other works by this author on:
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Chapter 5: Novel Nanotherapies for the Treatment of Coronary Atherosclerosisp110-149ByKurt Brassington;Kurt BrassingtonaInflammation and Cardiovascular Disease Laboratory, Baker Heart and Diabetes Institute,Melbourne, VIC,AustraliabBaker Department of Cardiometabolic Health, University of Melbourne,Parkville, VIC,AustraliaSearch for other works by this author on:Yi Ee Lye;Yi Ee LyeaInflammation and Cardiovascular Disease Laboratory, Baker Heart and Diabetes Institute,Melbourne, VIC,AustraliaSearch for other works by this author on:Alex Bobik;Alex BobikaInflammation and Cardiovascular Disease Laboratory, Baker Heart and Diabetes Institute,Melbourne, VIC,AustraliacCentre for Inflammatory Diseases, Department of Medicine, Monash Medical Centre,Clayton, VIC,AustraliadDepartment of Immunology, Monash University,Melbourne, VIC,AustraliaSearch for other works by this author on:Tin KyawTin KyawaInflammation and Cardiovascular Disease Laboratory, Baker Heart and Diabetes Institute,Melbourne, VIC,AustraliabBaker Department of Cardiometabolic Health, University of Melbourne,Parkville, VIC,AustraliacCentre for Inflammatory Diseases, Department of Medicine, Monash Medical Centre,Clayton, VIC,AustraliaE-mail: [email protected]Search for other works by this author on:
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Chapter 6: Advanced Nanomaterials for Cardiovascular Implantsp150-183ByI. Cicha;I. CichaaDepartment of Otolaryngology, Head and Neck Surgery, Section of Experimental Oncology and Nanomedicine (SEON), Else Kröner-Fresenius-Stiftung Professorship, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg,Erlangen,GermanyE-mail: [email protected]; [email protected]Search for other works by this author on:C. Alexiou;C. AlexiouaDepartment of Otolaryngology, Head and Neck Surgery, Section of Experimental Oncology and Nanomedicine (SEON), Else Kröner-Fresenius-Stiftung Professorship, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg,Erlangen,GermanySearch for other works by this author on:T. CiachT. CiachbWarsaw University of Technology, Faculty of Chemical and Process Engineering, Division of Biotechnology and Bioprocess Engineering, BioMedical Engineering Laboratory,Waryńskiego 1, 00-645 Warsaw,PolandcCentre for Advanced Materials and Technologies CEZAMAT, Warsaw University of Technology,Poleczki 19, 02-822, Warsaw,PolandSearch for other works by this author on:
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Chapter 7: Bioceramic-based Cardiovascular Implantsp184-196ByJ. KhaliqJ. KhaliqSearch for other works by this author on:
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Chapter 8: Targeted Gold Nanotherapy for the Attenuation of Chemotherapy-associated Cardiotoxicityp197-214ByF. Melia;F. MeliaaDepartment of Biochemistry and Biomedicine, School of Life Sciences, University of Sussex,Brighton,UKSearch for other works by this author on:Tanveer A. Tabish;Tanveer A. TabishbDivision of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford,Oxford,UKSearch for other works by this author on:M. Z. I. PranjolM. Z. I. PranjolaDepartment of Biochemistry and Biomedicine, School of Life Sciences, University of Sussex,Brighton,UKE-mail: [email protected]Search for other works by this author on:
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Chapter 9: Extracellular Vesicles for the Treatment of Cardiovascular Diseasesp215-255ByIqra Azhar;Iqra AzharSignal Transduction Laboratory, Quaid-i-Azam University,Islamabad, 45320,PakistanSearch for other works by this author on:Sana Karim;Sana KarimSignal Transduction Laboratory, Quaid-i-Azam University,Islamabad, 45320,PakistanSearch for other works by this author on:Ayesha Ishtiaq;Ayesha IshtiaqSignal Transduction Laboratory, Quaid-i-Azam University,Islamabad, 45320,PakistanSearch for other works by this author on:Iram MurtazaIram MurtazaSignal Transduction Laboratory, Quaid-i-Azam University,Islamabad, 45320,PakistanE-mail: [email protected]Search for other works by this author on:
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